Preparation, Characterization, and In Vitro Stability Analysis of Deer Sinew Peptide-Zinc Chelate.

Shan Yang, Tianyuan Liu, Weijia Chen, Ying Zong, Jianan Geng, Yan Zhao, Zhongmei He, Rui Du

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

Preparation of Deer Brain Peptide Chelated with Zinc and Its Effect on Improving Memory Impairment in Insomnia Mice Induced by Para-Chlorophenylalanine.Nutrients · 2026
Article
Food-Derived Zinc-Chelating Peptides: Coordination Chemistry, Intestinal Transport, and Nutritional Functionality.Nutrients · 2026
Review
Zinc Chelates from Low-Molecular-Weight Donkey-Hide Gelatin Peptides: Preparation, Characterization, and Evaluation of In Vitro Antioxidant Activity.Foods (Basel, Switzerland) · 2025
Article
Supplementation of zinc-chelating peptides fromFrontiers in nutrition · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shan YangCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Tianyuan LiuCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Weijia ChenCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Ying ZongCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Jianan GengCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Yan ZhaoCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.ORCID 0000-0003-0704-7410

Zhongmei HeCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.ORCID 0000-0002-2694-6510

Rui DuCollege of Traditional Chinese Medicines, Jilin Agricultural University, No. 2888, Xincheng Street, Changchun 130118, China.

Funding

Jilin Animal Husbandry Administration Sika Deer Antlers and Antlers and Fetal Bones into Food Project RJTG202402Jilin Science and Technology Development Talent Special Project: Study on the key technology and industrialization of chelating calcium from deer tendon under grant 20240601086RCStudy on key technology and industrialization of deer heart peptide product, a special diet that can increase exercise endurance 23JQ08the Academic Research Projects of the Jilin Province Major Science and Technology Special Project 20220304002YY, 20220304001YY

6 · The paper itself

Abstract

Novel peptide-zinc chelates (DSPs-Zn) with a zinc content of 186.94 mg/g were synthesized from deer tendon peptides at pH 6, 60 °C, 60 min, and peptide-zinc mass ratio of 1:3. Ultraviolet-visible absorption spectroscopy (UV) and Fourier transform infrared spectroscopy (FTIR) demonstrated that the chelation sites of the deer tendon polypeptides (DSPs) with zinc ions were located at the carboxyl oxygen and amino nitrogen atoms of the peptides. Amino acid analysis showed that aspartic acid, glutamic acid, lysine, and arginine play important roles in the chelation process. In vitro simulated gastrointestinal digestion studies showed that DSPs-zinc exhibited higher stability than zinc sulfate and zinc gluconate in the pH range 2-8 and in a simulated gastrointestinal digestion environment. The above experimental results suggest that DSPs-Zn has the potential to be used as a novel zinc nutritional supplement.

Indexed as

deer tendon proteinpeptides-zinc chelateresponse surface methodologysimulated gastrointestinal digestionstructural characterization

Identifiers

PMID40565740

DOI10.3390/foods14122131

PMCPMC12192407

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.