Mung Bean Protein Improves Hepatic Metabolic Homeostasis via Gut Microbiota Remodeling.

Kaining Han, Zhuoyao Deng, Guangxin Feng, Tanghao Li, Zhili Wan, Jian Guo, Xiaoquan Yang

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaining HanSchool of Medicine, Sun Yat-sen University, Guangzhou 510275, China.

Zhuoyao DengLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.

Guangxin FengLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.

Tanghao LiLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.ORCID 0000-0002-8915-1811

Zhili WanLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.ORCID 0000-0002-5865-4301

Jian GuoLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.

Xiaoquan YangLaboratory of Food Proteins and Colloids, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety, South China University of Technology, Guangzhou 510641, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2023A1515110652 and 2024A1515012167National Natural Science Foundation of China 32402080

6 · The paper itself

Abstract

Given the well-documented health benefits of plant proteins, mung bean protein has gained increasing attention as a promising plant-based protein source; however, its biofunctional properties have not been fully recognized. This study aimed to evaluate the hepatic metabolic regulatory effects of dietary mung bean protein in murine models, considering the central role of hepatic metabolic homeostasis in systemic regulation. The results demonstrated that dietary mung bean protein, both native mung bean protein isolate (MPI) and heat-denatured mung bean protein isolate (DMPI), restored hepatic metabolic homeostasis, an effect mediated by bioactive microbial metabolites. Notably, our results demonstrated that heat-induced denaturation of mung bean protein markedly alters its gut microbiota-regulating activity. This was evidenced by the observation that MPI tended to increase the abundance of

Indexed as

digestibilitygut microbiotahepatic metabolic homeostasismetabolitesmung bean protein

Identifiers

PMID40565680

DOI10.3390/foods14122070

PMCPMC12192330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.