Evidence map›Paper›PMID 40565599›Full record

ArticleGenes2025

Sara Cabet, Jean-François Ghersi-Egea, Suonavy Khung-Savatovsky, Fabien Guimiot, Audrey Putoux, Isabelle Sabatier, Carla Fernandez, Laure Raymond, Jérémie Mortreux, Hélène Laurichesse Delmas and 5 more

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Endoscopic third ventriculostomy for diencephalosynapsis-related hydrocephalus in MPDZ gene syndrome: a case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sara CabetPediatric and Fetal Imaging Department, Femme-Mère-Enfant Hospital, Hospices Civils de Lyon, Claude Bernard Lyon 1 University, 69500 Lyon, France.
Jean-François Ghersi-EgeaFluid Team, Lyon Neurosciences Research Center, CNRS UMR5292, INSERM U1028, Claude Bernard Lyon 1 University, 69500 Lyon, France.
Suonavy Khung-SavatovskyFunctional Unit of Fetal Pathology, Department of Genetics, Robert-Debré Hospital, AP-HP, 75019 Paris, France.ORCID 0000-0001-6476-6345
Fabien GuimiotFunctional Unit of Fetal Pathology, Department of Genetics, Robert-Debré Hospital, AP-HP, 75019 Paris, France.ORCID 0000-0002-0811-9538
Audrey PutouxDepartment of Genetics, Groupement Hospitalier Est, Hospices Civils de Lyon, Claude Bernard Lyon 1 University, 69500 Lyon, France.ORCID 0000-0001-5496-4604
Isabelle SabatierDepartment of Pediatric Neurology, Femme-Mère-Enfant Hospital, Hospices Civils de Lyon, 69500 Lyon, France.
Carla FernandezDepartment of Pathology, Felix Guyon Hospital, 97490 Saint-Denis, France.
Laure RaymondGenetic Department, Eurofins Biomnis, 69500 Lyon, France.
Jérémie MortreuxGenetic Department, Eurofins Biomnis, 69500 Lyon, France.ORCID 0000-0002-2914-1961
Hélène Laurichesse DelmasMultidisciplinary Prenatal Diagnosis Center, University Hospital Center of Clermont Ferrand, 63000 Clermont Ferrand, France.
Fabrice Eric CuillierFetal Imaging Department, Felix Guyon Hospital, 97490 Saint-Denis, France.
Fabien HoImagerie Capricorne, Clinique Sainte-Clotilde, 97490 Saint-Denis, France.
Gaetan LescaInstitut NeuroMyoGène, CNRS UMR5292, INSERM U1028, Claude Bernard Lyon 1 University, 69500 Lyon, France.ORCID 0000-0001-7691-9492
Jean-Luc AlessandriGenetic Department, Felix Guyon Hospital, La Réunion University, 97490 Saint-Denis, France.
Laurent GuibaudPediatric and Fetal Imaging Department, Femme-Mère-Enfant Hospital, Hospices Civils de Lyon, Claude Bernard Lyon 1 University, 69500 Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVentriculomegaly is the main prenatal imaging feature for diagnosing fetal central nervous system anomalies in humans. Many ventriculomegalies can be related to genetic causes, regardless of their imaging presentations. Among these,

methodsTo address this question, we retrospectively analyzed pre- and postnatal neuro-imaging and neuropathological data for cases of ventriculomegaly in which

resultsWe analyzed six cases (four fetuses and two children) of ventriculomegaly of variable severities with

conclusionsThe morphological analysis using targeted brain magnetic resonance imaging (MRI) and neuropathological data allowed us to unravel the underlying mechanisms of congenital ventriculomegaly related to

Indexed as

HydrocephalusThird VentricleFemaleFetusHumansInfant, NewbornMagnetic Resonance ImagingMaleMutationPregnancyRetrospective StudiesdiencephalosynapsishydrocephalusMPDZthalamusthird ventricleventriculomegaly

Identifiers

PMID40565599
PMCPMC12192413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.