Evidence map›Paper›PMID 40565535›Full record

ReviewGenes2025

Collagen Type IV Variants and Kidney Cysts: Decoding the COL4A Puzzle.

Matteo Rigato, Carlotta Caprara, J Said Cabrera-Aguilar, Nenzi Marzano, Anna Giuliani, Barbara Mancini, Fiorella Gastaldon, Claudio Ronco, Monica Zanella, Daniela Zuccarello and 1 more

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. TargetingbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matteo RigatoDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0000-0001-9008-9368
Carlotta CapraraDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0000-0002-6945-4460
J Said Cabrera-AguilarThe International Renal Research Institute of Vicenza (IRRIV) Foundation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.
Nenzi MarzanoThe International Renal Research Institute of Vicenza (IRRIV) Foundation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0009-0005-9225-4036
Anna GiulianiDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.
Barbara ManciniDepartment of Medical Genetics and Genomics, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0009-0002-7000-4907
Fiorella GastaldonDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.
Claudio RoncoThe International Renal Research Institute of Vicenza (IRRIV) Foundation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0000-0002-6697-4065
Monica ZanellaDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.
Daniela ZuccarelloDepartment of Medical Genetics and Genomics, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.ORCID 0000-0001-5826-6715
Valentina CorradiDepartment of Nephrology, Dialysis and Transplantation, AULSS8 BERICA, San Bortolo Hospital, 36100 Vicenza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic variants in type IV collagen genes (

Indexed as

Collagen Type IVKidney Diseases, CysticNephritis, HereditaryAnimalsHumansMiceCOL4A4 protein, humanCollagen Type IVADPKDAlport syndromeCOL4Acollagen variantscystic kidney diseasekidney cysts

Identifiers

PMID40565535
PMCPMC12193310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.