Evidence map›Paper›PMID 40565512›Full record

ArticleGenes2025

Automated Quantitative Immunofluorescence Microscopy Approach for Diagnosis of Hereditary Thrombopathies: A Proof of Concept Using Bernard-Soulier Syndrome and Glanzmann Thrombasthenia.

Kevin Loos, Rawya Al-Rifai, Sandra Ohlenforst, Claudia Klein, Johannes Oldenburg, Anna Pavlova, Behnaz Pezeshkpoor

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin LoosInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.
Rawya Al-RifaiInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.
Sandra OhlenforstInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.
Claudia KleinInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.
Johannes OldenburgInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.ORCID 0000-0002-1585-4100
Anna PavlovaInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.
Behnaz PezeshkpoorInstitute of Experimental Hematology and Transfusion Medicine, University Clinic Bonn, 53127 Bonn, Germany.ORCID 0000-0002-4796-3424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited platelet disorders (IPDs) are rare bleeding disorders characterized by impaired platelet function and/or reduced blood platelet count. Their diagnosis typically relies on complex laboratory methods, including flow cytometry, aggregometry, and molecular genetic analysis. In recent years, immunofluorescence microscopy has been established as an alternative diagnostic method for IPDs.

Indexed as

Bernard-Soulier SyndromeThrombastheniaAdultBlood PlateletsChildFemaleFlow CytometryHumansMaleMicroscopy, FluorescenceProof of Concept Studyautomated diagnosisBernard–Soulier syndromeflow cytometryGlanzmann thrombastheniaimmunofluorescence microscopyinherited platelet disordersthrombocytopathy

Identifiers

PMID40565512
PMCPMC12192073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.