Evidence map›Paper›PMID 40565489›Full record

ArticleHealthcare (Basel, Switzerland)2025

Phase Angle Trajectory Among Critical Care Patients: Longitudinal Decline Predicts Mortality Independent of Clinical Severity Scores.

Pantelis Papanastasiou, Stavroula Chaloulakou, Dimitrios Karayiannis, Avra Almperti, Georgios Poupouzas, Charikleia S Vrettou, Vasileios Issaris, Edison Jahaj, Alice G Vassiliou, Ioanna Dimopoulou

Abstract read
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Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pantelis PapanastasiouDepartment of Clinical Nutrition, Evangelismos General Hospital, 10676 Athens, Greece.ORCID 0000-0001-8076-1966
Stavroula ChaloulakouDepartment of Clinical Nutrition, Evangelismos General Hospital, 10676 Athens, Greece.ORCID 0009-0008-8499-7712
Dimitrios KarayiannisDepartment of Clinical Nutrition, Evangelismos General Hospital, 10676 Athens, Greece.ORCID 0000-0003-4142-2392
Avra AlmpertiDepartment of Clinical Nutrition, Evangelismos General Hospital, 10676 Athens, Greece.
Georgios PoupouzasPulmonary Department, Evangelismos General Hospital, 10676 Athens, Greece.ORCID 0009-0000-2804-1208
Charikleia S Vrettou1st Department of Critical Care Medicine, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 10676 Athens, Greece.ORCID 0000-0002-1067-8849
Vasileios IssarisPulmonary Department, Evangelismos General Hospital, 10676 Athens, Greece.ORCID 0000-0001-6107-9400
Edison Jahaj1st Department of Critical Care Medicine, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 10676 Athens, Greece.ORCID 0000-0002-7306-713X
Alice G Vassiliou1st Department of Critical Care Medicine, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 10676 Athens, Greece.ORCID 0000-0003-4984-0476
Ioanna Dimopoulou1st Department of Critical Care Medicine, School of Medicine, National and Kapodistrian University of Athens, Evangelismos Hospital, 10676 Athens, Greece.ORCID 0000-0002-2219-7292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe phase angle (PhA) is an emerging biomarker reflecting the cellular integrity and nutritional status. This study aimed to explore potential associations between the PhA, clinical severity scores, and 60-day survival outcomes following an admission to the Intensive Care Unit (ICU).

methodsThis prospective, single-center study included 43 critically ill patients admitted to the ICU at Evangelismos General Hospital between May and November 2024. Patients were stratified by their PhA (≤5.4° vs. >5.4°). The PhA was measured at admission and subsequently on days 5-7, 10-11, 13-14, and until discharge. Severity scores (SOFA and APACHE II) were recorded. Between-group differences were assessed using independent samples

resultsThe mean age was 54.6 ± 17 years; 63.6% were male. At ICU admission, patients with a PhA > 5.4° were significantly younger (

conclusionsWhile limited by a small sample size and single-center design, these findings support the further exploration of the PhA as a monitoring tool in critical care.

Indexed as

APACHE II scorebio-impedance analysisICUlong-term mortalityphase angleSOFA score

Identifiers

PMID40565489
PMCPMC12192603

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