Evidence map›Paper›PMID 40565306›Full record

ReviewInternational journal of molecular sciences2025

The Role of MicroRNA in the Pathogenesis of Atopic Dermatitis.

Natalia Gołuchowska, Aldona Ząber, Agata Będzichowska, Agata Tomaszewska, Agnieszka Rustecka, Bolesław Kalicki

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia GołuchowskaDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Aldona ZąberDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.ORCID 0009-0004-3577-3203
Agata BędzichowskaDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Agata TomaszewskaDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.ORCID 0000-0003-3255-7623
Agnieszka RusteckaDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Bolesław KalickiDepartment of Pediatrics, Pediatric Nephrology and Allergology, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.ORCID 0000-0003-1606-5100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczematous lesions and recurrent pruritus. The pathogenesis of AD involves epidermal barrier impairments, immune dysfunction, and both genetic and environmental factors. This review presents the latest findings regarding the involvement of microRNA (miRNA) molecules in AD pathogenesis and their potential application as diagnostic biomarkers and therapeutic targets. The following miRNAs were analyzed in detail: miR-223, miR-10a-5p, miR-29b, miR-146a-5p, miR-451a, miR-124, miR-143, miR-151a, miR-24, miR-191, and miR-155. Their molecular mechanisms and potential clinical implications are discussed. Understanding the role of specific microRNAs in AD pathogenesis may contribute to the development of new diagnostic and therapeutic strategies for this disease.

Indexed as

Dermatitis, AtopicMicroRNAsAnimalsBiomarkersGene Expression RegulationHumansBiomarkersMicroRNAsatopic dermatitisbiomarkersmiRNATh2-dependent inflammationtreatment

Identifiers

PMID40565306
PMCPMC12193253

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.