Evidence map›Paper›PMID 40565170›Full record

ArticleInternational journal of molecular sciences2025

The Effects of Lutein-Containing Supplement Intake on Glycation Inhibition Among Diabetic Patients with Cataracts.

Rijo Hayashi, Shimmin Hayashi, Shigeki Machida

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rijo HayashiDepartment of Ophthalmology, Saitama Medical Center, Dokkyo Medical University, Koshigaya 343-8555, Saitama, Japan.ORCID 0000-0002-1575-3967
Shimmin HayashiDepartment of Ophthalmology, Saitama Medical Center, Dokkyo Medical University, Koshigaya 343-8555, Saitama, Japan.
Shigeki MachidaDepartment of Ophthalmology, Saitama Medical Center, Dokkyo Medical University, Koshigaya 343-8555, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycation is known as an important factor inducing human diseases, including diabetic complications. As oxidative stress contributes to procedures of glycation, antioxidants may inhibit glycation and delay the progression of diabetic complications. Our previous investigation of human aqueous humor after the intake of a lutein-containing supplement demonstrated increases in antioxidative activities and decreases in peroxidative products. This study enrolled 25 patients with diabetes (DM group) and 100 age-matched controls. Aqueous humor samples were collected during cataract surgery before and after 6 weeks of oral intake of the lutein-containing antioxidant supplement, Ocuvite + Lutein

Indexed as

AntioxidantsCataractDiabetes ComplicationsDietary SupplementsLuteinAgedCase-Control StudiesFemaleGlycation End Products, AdvancedGlycosylationHumansLysineMaleMiddle AgedOxidative StressSuperoxide DismutaseAntioxidantsGlycation End Products, AdvancedLuteinLysineN(6)-carboxymethyllysineSuperoxide Dismutaseadvanced glycation end productsantioxidantaqueous humordiabetesglycationluteinsenile cataract

Identifiers

PMID40565170
PMCPMC12193149

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.