Evidence map›Paper›PMID 40565102›Full record

ArticleInternational journal of molecular sciences2025

Cold-Sensing TRP Channels and Temperature Preference Modulate Ovarian Development in the Model Organism

Gabriele Andreatta, Sara Montagnese, Rodolfo Costa

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Thermo-Sensitive Molecular Switch:International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriele AndreattaDepartment of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-8857-7282
Sara MontagneseDepartment of Medicine, University of Padua, 35128 Padua, Italy.ORCID 0000-0003-2800-9923
Rodolfo CostaChronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.ORCID 0000-0002-2489-9116

Funding

CaRiPaRo NADepartment of Biology at the University of Padua Junior Research FellowshipEU Horizon 2020 Comparative Insect Chronobiology (CINCHRON), Marie Sklodowska-Curie Initial Training NetworkEU Horizon 2020 DECISION-EU (Call H2020-SC1-BHC-2018-2020)EU Horizon 2020 project 101169474 - INCITE. Horizon-MSCA-2023-DN-01Marie Sklodowska-Curie Actions Postdoctoral fellowship (Project N° 101109842)
6 · The paper itself

Abstract

Temperature is perceived primarily via transient receptor potential (TRP) channels, which are integral to the molecular machinery sensing environmental and cellular signals. Functional evidence of TRP channels' involvement in regulating cold-induced developmental/reproductive responses remains scarce. Here, we show that mutations affecting cold-sensing TRP channels antagonize the reduction in ovarian development induced by low temperatures (reproductive dormancy) in

Indexed as

Drosophila melanogasterDrosophila ProteinsOvaryTransient Receptor Potential ChannelsAnimalsCold TemperatureFemaleMutationOocytesThermosensingDrosophila ProteinsTransient Receptor Potential Channelsovarian developmentreproductive dormancytemperature preferencetemperature sensingTRP channels

Identifiers

PMID40565102
PMCPMC12192652

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.