Evidence map›Paper›PMID 40564998›Full record

SynthesisInternational journal of molecular sciences2025

Aggressive Thyroid Carcinomas Clinical and Molecular Features: A Systematic Review.

Sorina Schipor, Mihai Alin Publik, Dana Manda, Mihail Ceausu

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Aggressive follicular cell derived thyroid carcinoma: what do you need from the pathologist.Virchows Archiv : an international journal of pathology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Multilayered Insights into Poorly Differentiated,Diagnostics (Basel, Switzerland) · 2025
    Article
  11. Multimodal spectrum of approach in poorly differentiated thyroid carcinoma (an updated analysis).Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sorina SchiporDepartment of Research, "C.I. Parhon" National Institute of Endocrinology, 011863 Bucharest, Romania.
Mihai Alin PublikDepartment of Pathology, "C.I. Parhon" National Institute of Endocrinology, 011863 Bucharest, Romania.ORCID 0000-0002-6943-8444
Dana MandaDepartment of Research, "C.I. Parhon" National Institute of Endocrinology, 011863 Bucharest, Romania.
Mihail CeausuDepartment of Pathology, "C.I. Parhon" National Institute of Endocrinology, 011863 Bucharest, Romania.ORCID 0000-0003-2655-8160

Funding

Ministry of Research, Innovation and Digitization, CCCDI-UEFISCDI project number PN-IV-P7-7.1-PED-2024-0307
6 · The paper itself

Abstract

Aggressive thyroid carcinomas are rare malignancies characterized by a high impact on patient's lives and poor prognosis. The available literature is scarce presenting divergent data concerning the clinical outcomes, prognostic factors and variable mutational signature studies. We aim to collect data from the literature and assemble a systematic review. The literature from 2007 until May 2025 was searched using PubMed. Studies bearing data concerning clinical aspects, prognostic outcomes, or molecular characteristics of differentiated high-grade (DHGTC), poorly differentiated (PDTC), and anaplastic thyroid carcinomas (ATC) were retrieved. Original articles in English, ethically conducted on human patients, were selected. From 688 articles, 39 were included.

Indexed as

Thyroid Carcinoma, AnaplasticThyroid NeoplasmsBiomarkers, TumorHumansMutationPrognosisBiomarkers, TumoraggressiveanaplasticATCDHGTCdifferentiated high gradePDTCpoorly differentiatedthyroid carcinoma

Identifiers

PMID40564998
PMCPMC12192656

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.