Evidence map›Paper›PMID 40564979›Full record

ArticleInternational journal of molecular sciences2025

Effects of Sodium Alginate Infusion on Intramammary Immunity Against Subclinical Mastitis in Dairy Cows.

Yu-I Pan, Yu-Chia Lin, Jai-Wei Lee, Perng-Chih Shen, Rolissa Ballantyne, Hsu-Hsun Lee, Kuo-Hua Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-I PanDepartment of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.ORCID 0009-0006-6979-5026
Yu-Chia LinDepartment of Animal Science, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.
Jai-Wei LeeDepartment of Tropical Agriculture and International Cooperation, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.
Perng-Chih ShenDepartment of Animal Science, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.ORCID 0000-0002-9901-5274
Rolissa BallantyneDepartment of Tropical Agriculture and International Cooperation, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.ORCID 0000-0003-1703-7566
Hsu-Hsun LeeDepartment of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912301, Taiwan.ORCID 0000-0002-9651-6831
Kuo-Hua LeeNorthern Region Branch, Taiwan Livestock Research Institute, Ministry of Agriculture, Miaoli 368003, Taiwan.

Funding

Taiwan Agrimann Company B112411
6 · The paper itself

Abstract

Mastitis is a major issue in dairy cows, with subclinical mastitis (SCM) being hard to detect and potentially progressing to clinical mastitis. Antibiotic use raises concerns about resistance and milk contamination, highlighting the need for natural alternatives. Sodium alginate (SA), known for its antioxidant and immunomodulatory properties, may offer a solution, though its effects on mastitis are unclear. Intramammary infusion of 1% SA (30 mL) was tested in both healthy cows (

Indexed as

AlginatesMammary Glands, AnimalMastitis, BovineAnimalsCattleCytokinesFemaleMilkAlginatesCytokinesdairy cowsimmune modulationsodium alginatesomatic cell countsubclinical mastitis

Identifiers

PMID40564979
PMCPMC12192673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.