Evidence map›Paper›PMID 40564904›Full record

ReviewInternational journal of molecular sciences2025

The Role of the RecFOR Complex in Genome Stability.

Piero R Bianco

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Nanoscale Analysis of SSB-RecO Interplay in SSB Interaction with the Target.International journal of molecular sciences · 2026
    Article
  2. Actuation of CRP activating region 3 by formylation modulates theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Piero R BiancoDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198-6025, USA.ORCID 0000-0003-2974-7952

Funding

Insight into the mechanism of action of the SSB interactomeR01GM144414 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LYUBCHENKO, YURI L · 2022 to 2025
$1.5M
NIGMS NIH HHS R01 GM144414NIH HHS 1R01TW144414-23
6 · The paper itself

Abstract

The maintenance of genome stability requires the coordinated actions of multiple proteins and protein complexes. One critical family of proteins is the recombination mediators. Their role is to facilitate the formation of recombinase nucleoprotein filaments on single-stranded DNA (ssDNA). Filament formation can take place on post-replicative ssDNA gaps as well as on 3'-tailed duplexes resulting from helicase-nuclease processing. In prokaryotes, the RecF, O, and R proteins are widely distributed and mediate RecA loading as either the RecFOR or RecOR complexes, depending on the species being studied. In this review, I compare and contrast the available biochemical and structural information to provide insight into the mechanism of action of this critical family of mediators.

Indexed as

Genomic InstabilityDNA, Single-StrandedRec A RecombinasesDNA, Single-StrandedRec A RecombinasesDNA repairgenetic recombinationRecFRecOrecombination mediatorRecRSSB protein

Identifiers

PMID40564904
PMCPMC12192639

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.