ArticleDiagnostics (Basel, Switzerland)2025
Causal Relationship Between Cerebrospinal Fluid Metabolites and Intervertebral Disc Disease: A Bidirectional Mendelian Randomization Study.
Jiheng Xiao, Tianyi Xia, Xianglong Zhou, Xin Xing, Yanbin Zhu, Yingze Zhang, Liming Xiong
Abstract read
In one paragraphArticle in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Jiheng XiaoDepartment of Orthopaedics, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan 430022, China.ORCID 0000-0003-1133-4703 Tianyi XiaDepartment of Orthopaedics, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan 430022, China.
Xianglong ZhouDepartment of Orthopaedics, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan 430022, China.
Xin XingDepartment of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
Yanbin ZhuDepartment of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
Yingze ZhangDepartment of Orthopaedics, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan 430022, China.
Liming XiongDepartment of Orthopaedics, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan 430022, China.ORCID 0000-0002-9003-4671 Funding
Huazhong University of Science and Technology 19th Batch of Graduate Student Innovation Fund Project 2021yjsCXCY119Hubei Xianning Science and Technology Program Project 2023GXYF102the Hygiene and Health Innovation Project of Major project assignment for research and development in Hebei province 21377731Dthe Integration Project of NSFC Joint Fund for Regional Innovation and Development U23A6008the Key Projects of the National Natural Science Foundation of China 32130052
6 · The paper itselfAbstract
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Indexed as
causal inferencecerebrospinal fluid metabolitesintervertebral disc degenerationmendelian randomization
Identifiers
PMID40564845
PMCPMC12191516
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