Evidence map›Paper›PMID 40564695›Full record

ArticleChildren (Basel, Switzerland)2025

Orofacial Myofunctional Therapy: Investigating a Novel Therapeutic Approach for Pediatric Obstructive Sleep Apnea in Children with and Without Down Syndrome-A Study Protocol.

Jolien Verbeke, Iris Meerschman, Karlien Dhondt, Els De Leenheer, Julie Willekens, Kristiane Van Lierde, Sofie Claeys

Abstract read
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Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jolien VerbekeDepartment of Rehabilitation Sciences, Centre for Speech and Language Sciences (CESLAS), Ghent University, Corneel Heymanslaan 10, 2P1, 9000 Ghent, Belgium.ORCID 0000-0003-3558-6577
Iris MeerschmanDepartment of Rehabilitation Sciences, Centre for Speech and Language Sciences (CESLAS), Ghent University, Corneel Heymanslaan 10, 2P1, 9000 Ghent, Belgium.ORCID 0000-0003-1147-1708
Karlien DhondtDepartment of Child & Adolescent Psychiatry, Pediatric Sleep Center, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.ORCID 0000-0002-0688-026X
Els De LeenheerDepartment of Otorhinolaryngology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.ORCID 0000-0002-2789-3529
Julie WillekensDepartment of Pediatric Pulmonology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.ORCID 0009-0002-3422-9535
Kristiane Van LierdeDepartment of Rehabilitation Sciences, Centre for Speech and Language Sciences (CESLAS), Ghent University, Corneel Heymanslaan 10, 2P1, 9000 Ghent, Belgium.
Sofie ClaeysDepartment of Otorhinolaryngology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

Funding

Research Fund Flanders 11PLT24N
6 · The paper itself

Abstract

BACKGROUND/

objectivesPediatric obstructive sleep apnea (OSA) is a prevalent medical condition, affecting 1-5% of non-syndromic children and 30-90% of children with Down syndrome. Given the severity of the condition and the associated health risks, early and effective treatment is crucial. However, current treatment modalities are often invasive or suffer from poor patient adherence. Additionally, adenotonsillectomy, the first-line treatment in pediatric OSA, seems not to be effective in every child, leaving children with residual OSA postoperatively. These challenges are particularly pronounced in high-risk populations, such as children with Down syndrome, highlighting the need for alternative therapeutic strategies. Therefore, a protocol is presented to evaluate the effectiveness of orofacial myofunctional therapy (OMT) as a treatment for OSA in two pediatric populations: (1) Non-syndromic children aged 4-18 years: 10 weeks of OMT. (2) Children with Down syndrome aged 4-18 years: 20 weeks of OMT. Effects of the OMT program will be evaluated on: sleep parameters (e.g., obstructive Apnea-Hyponea Index (oAHI), snoring frequency); orofacial functions (e.g., breathing pattern, tongue position at rest); quality of life outcomes.

methodsA pretest-posttest design will be used to evaluate the effectiveness of OMT in both children with and without Down syndrome and OSA. Both objective measures and patient-reported outcomes are being collected.

resultsOMT is expected to improve orofacial functions, reduce OSA severity and symptoms, and enhance quality of life in both non-syndromic and syndromic children.

conclusionsThis multidisciplinary research protocol, involving collaboration between ENT specialists and speech-language pathologists, aims to provide a comprehensive understanding of the potential benefits of OMT in treating OSA.

Indexed as

down syndromemultidisciplinary researchobstructive sleep apneaorofacial myofunctional therapyoropharyngeal exercises

Identifiers

PMID40564695
PMCPMC12191010

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