Moving Away from One-Size-Fits-All: Assessing the Use of Pharmacogenetic-Guided Medication Therapy in Pediatric Patients with Chronic Pain.

Danielle Ruskin, Klaudia Szczech, Sierra Scodellaro, Naiyi Sun, Iris Cohn

Abstract read

In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danielle RuskinDepartment of Psychology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

Klaudia SzczechDepartment of Psychology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.ORCID 0000-0002-7493-4557

Sierra ScodellaroDivision of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.ORCID 0009-0008-5871-3085

Naiyi SunDepartment of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

Iris CohnDivision of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.

Funding

SickKids Foundation Precision Child Health Catalyst Grant

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic pain servicepediatric chronic painpharmacogenetics (PGx)precision medicinequalitative analysis

Identifiers

PMID40564679

DOI10.3390/children12060721

PMCPMC12191342

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.