ArticleChildren (Basel, Switzerland)2025
Effectiveness of Bundled Interventions for the Prevention of Neonatal Hypothermia in Low-Income Settings: A Quality Improvement Project in a Referral Hospital in Ethiopia.
Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of neonatal intensive care in Africa: a systematic review and meta-analysis.BMC health services research · 2026Pooled it
- Neonatal Hypothermia in Mogadishu, Somalia: Strengthening Thermal Care Beyond NICU Equipment.Research and reports in tropical medicine · 2026Article
- Preventing Perioperative Hypothermia in Neonatal Surgical Patients: A Phased Quality Improvement Initiative within the Wake Up Safe Collaborative.Pediatric quality & safetyArticle
- Admission Hypothermia and Neonatal Mortality in the Ethiopian Neonatal Network.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypothermia at admission and in the following days is a major risk factor for neonatal mortality in both high- and low-resource settings. Implementing hypothermia prevention procedures is not an easy goal to achieve, and the few studies currently available in low-income countries focus mainly on temperature at admission. Deviation from normothermia does not exhaust its effects upon admission, with a demonstrated negative impact of hypothermia also during the first days of life.
objectiveThe aim of this study was to evaluate the effectiveness of bundled interventions in preventing neonatal hypothermia at admission and during hospitalization in a low-resource setting.
methodsThis was a retrospective, observational, before-after study comparing a pre- (December 2023-February 2024) and a post-quality improvement intervention period (April-June 2024). The outcome measures included admission temperature, average temperature during hospitalization, number of hypothermia episodes, temperature checks per day during hospitalization, and mortality.
resultsFrom the pre- to the post-intervention period, the median admission temperature increased from 35.6 °C to 36.0 °C (
conclusionsIn a Sub-Saharan referral hospital, the implementation of bundled interventions to maintain the warm chain improved neonatal temperature at admission and during hospitalization, and reduced hypothermia episodes during hospitalization.
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