ArticleAnimals : an open access journal from MDPI2025
Effects of Alpha-Ketoglutarate Supplementation on Growth Performance, Diarrhea Incidence, Plasma Amino Acid, and Nutrient Digestibility in Weaned Piglets.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Glutamine and Its Precursors Supplementation Improve Growth Performance and Immunity and Regulate Gastrointestinal Microbiota of Suckling Lambs.Life (Basel, Switzerland) · 2026Article
- Alpha-Ketoglutarate: A Metabolic Regulator of Cellular Homeostasis and Pathophysiology.Biomedicines · 2026Review
- Effects of Dietary Alpha-Ketoglutarate Supplementation on Diarrhea Incidence and Nutrient Digestibility in Weaned Piglets Fed Low-Protein Diets.Veterinary sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alpha-ketoglutaric acid (AKG) is a key intermediate in the tricarboxylic acid cycle and plays a crucial role in energy production and amino acid metabolism. This study aimed to evaluate the effects of AKG on growth performance, nutrient digestibility, plasma biochemical parameters, and plasma amino acid profiles in weaned piglets. A total of 72 weaned piglets with an average weight of 7.33 kg (±0.50 kg) and an average age of 28 (±2 days) were randomly assigned to 3 dietary treatments with 6 replicates per group in a 42-day trial. The treatments included a basal diet (CT), a basal diet with 500 g/t AKG (AKG1), and a basal diet with 1000 g/t AKG (AKG2). Blood samples were collected on days 14 and 42, and fecal samples were collected on day 42. The results showed that diets including 500 g/t and 1000 g/t AKG significantly reduced diarrhea incidence in piglets compared to the CT group (
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Registered trials
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