Evidence map›Paper›PMID 40564268›Full record

ArticleAnimals : an open access journal from MDPI2025

Clinical and Clinico-Pathological Observations of the Erythrocyte Sedimentation Rate in Dogs Affected by Leishmaniosis and Monitored During Antileishmanial Treatment.

George Lubas, Saverio Paltrinieri, Roberto Amerigo Papini, Ilaria Lensi, Silvia Benali, Oscar Cortadellas, Alessandra Fondati, Xavier Roura, Eric Zini

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

George LubasClinica Veterinaria Colombo, VetPartners Italia, V.le Colombo 153, Lido di Camaiore, 55041 Lucca, Italy.ORCID 0000-0002-9430-1060
Saverio PaltrinieriDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-7117-7987
Roberto Amerigo PapiniDepartment of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56124 Pisa, Italy.ORCID 0000-0002-5928-0663
Ilaria LensiClinica Veterinaria Colombo, VetPartners Italia, V.le Colombo 153, Lido di Camaiore, 55041 Lucca, Italy.ORCID 0009-0007-4132-5396
Silvia BenaliMYLAV, Laboratorio La Vallonea, Via G. Sirtori, 9, Passirana di Rho, 20017 Milano, Italy.ORCID 0009-0006-5916-1644
Oscar CortadellasHospital Clínico Veterinario, Universidad CEU Cardenal Herrera, 46115 Valencia, Spain.ORCID 0000-0002-7144-8318
Alessandra FondatiVeterinaria Cetego, Via M.C. Cetego 20, 00177 Roma, Italy.ORCID 0009-0002-2202-214X
Xavier RouraHospital Clínic Veterinari, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0002-1098-2381
Eric ZiniAniCura Istituto Veterinario Novara, Strada Provinciale 9, 28060 Granozzo con Monticello, Italy.ORCID 0000-0002-7580-1297

Funding

DIESSE Diagnostica Senese S.p.A. Società Benefit (Italy) no data
6 · The paper itself

Abstract

The erythrocyte sedimentation rate (ESR) is used in canine medicine in several disorders, especially to evaluate the levels of inflammation. ESR is a valid inflammatory marker in canine leishmaniosis (CanL), being markedly increased in sick dogs. This study evaluated the ESR together with several other inflammatory and immune response markers in 43 dogs affected by severe leishmaniosis, treated with antileishmanial treatment. Dogs were monitored at the beginning (T1) of treatment, in the middle (T2) of treatment, and 7-10 days after the end of the treatment (T3). The antileishmanial treatment was based on meglumine antimoniate and allopurinol for four weeks plus adding prednisolone at the anti-inflammatory dosage progressively tapered within the T2 set point. The ESR was measured and compared to immune and/or inflammatory markers (C-reactive protein, fibrinogen, ferritin, gamma-globulins, IgG). ESR levels were statistically reduced during treatment and significantly decreased at the end of the treatment. This came along with an improvement in other blood markers. This study shows the utility of ESR as a point-of-care test that can be used to monitor the response of dogs to antileishmanial treatment.

Indexed as

canineerythrocyte sedimentation rateimmune response markersinflammatory markersleishmaniosis

Identifiers

PMID40564268
PMCPMC12189301

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.