Evidence map›Paper›PMID 40564257›Full record

ArticleAnimals : an open access journal from MDPI2025

Identification of Two Genetic Haplotypes Associated with the Roan Coat Color in the American Quarter Horse and Other Equine Breeds.

Robin E Everts, Rachael Caron, Gabriel Foster, Kaitlyn McLoone, Katie Martin, Samantha A Brooks, Christa Lafayette

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robin E EvertsEtalon Inc., Menlo Park, CA 94025, USA.ORCID 0009-0001-3977-2089
Rachael CaronEtalon Inc., Menlo Park, CA 94025, USA.
Gabriel FosterEtalon Inc., Menlo Park, CA 94025, USA.
Kaitlyn McLooneEtalon Inc., Menlo Park, CA 94025, USA.
Katie MartinEtalon Inc., Menlo Park, CA 94025, USA.
Samantha A BrooksDepartment of Animal Sciences, UF Genetics Institute, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-4500-2689
Christa LafayetteEtalon Inc., Menlo Park, CA 94025, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The roan coat color is described as the dispersion of white hairs within an otherwise solid background color coat. This phenotype is primarily expressed on the body of the horse, with the head and legs exhibiting few to no white hairs. Previous studies mapped the locus for roan to the KIT region and observed linked variants in a small number of breeds. However, utilizing those linked markers to determine the roan genotype in other breeds has seen limited success. In this communication we identify a second roan allele (RN2) which, in conjunction with a previously observed roan allele (RN1) discovered in previous studies, accounts for approximately 74%, or 188 horses, out of a sample size totaling 257 roan horses. These two alleles were present in the non-roan population (N = 3212) at less than 1%, only in horses with light coat color and dilution alleles, likely obscuring the roan phenotype. Future work is required to identify additional alleles responsible for additional roan-type horse coat color phenotypic variation.

Indexed as

horsesKITroan

Identifiers

PMID40564257
PMCPMC12189688

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.