Evidence map›Paper›PMID 40564221›Full record

ArticleBiomedicines2025

Pyridostigmine Mitigates Methotrexate-Induced Liver Fibrosis in Rats: Association with Changes in BMP-9, SIRT1, and Endoglin Expression.

Mehmet Ulusan, Mumin Alper Erdogan, Ozkan Simsek, Hilal Ustundag, Zafer Dogan, Bertug Bekir Ciftci, Mesih Kocamuftuoglu, Imdat Orhan, Oytun Erbas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mehmet UlusanDepartment of Internal Medicine, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur 15030, Turkey.
Mumin Alper ErdoganDepartment of Physiology, Faculty of Medicine, Izmir Katip Celebi University, Izmir 35620, Turkey.ORCID 0000-0003-0048-444X
Ozkan SimsekDepartment of Physiology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur 15030, Turkey.ORCID 0000-0003-3340-9382
Hilal UstundagDepartment of Physiology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan 24100, Turkey.
Zafer DoganDepartment of Surgery, Faculty of Veterinary Medicine, Tekirdag Namik Kemal University, Tekirdag 59010, Turkey.
Bertug Bekir CiftciDepartment of Veterinary Surgery, Health Science Institute, Erciyes University, Kayseri 38280, Turkey.
Mesih KocamuftuogluDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur 15030, Turkey.
Imdat OrhanDepartment of Anatomy, Faculty of Veterinary Medicine, Erciyes University, Kayseri 38280, Turkey.ORCID 0009-0000-4450-0371
Oytun ErbasFaculty of Medicine, Biruni Research Center (BAMER), Biruni University, Istanbul 34015, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

fibrosisliver injurymethotrexateoxidative stresspyridostigminesirtuin 1

Identifiers

PMID40564221
PMCPMC12190876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.