Evidence map›Paper›PMID 40564046›Full record

ReviewBiomedicines2025

A Narrative Review of Current and Investigational Therapies in Hypertrophic Cardiomyopathy.

Ian Ogurek, Randeep Gill, Vasiliki Tasouli-Drakou, Ronnie Joseph, Arbab Khalid, Nazanin Houshmand, Tahir Tak

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ian OgurekDepartment of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89106, USA.
Randeep GillDepartment of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89106, USA.
Vasiliki Tasouli-DrakouDepartment of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89106, USA.ORCID 0000-0002-5011-8125
Ronnie JosephDepartment of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89106, USA.
Arbab KhalidDepartment of Internal Medicine, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, NV 89106, USA.
Nazanin HoushmandDepartment of Cardiovascular Medicine, University of Nevada, Las Vegas, NV 89106, USA.
Tahir TakDepartment of Cardiovascular Medicine, University of Nevada, Las Vegas, NV 89106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy is the most prevalent inherited cardiac condition, distinguished by an autosomal dominant inheritance pattern. Diagnosis can be achieved through echocardiography, cardiac magnetic resonance imaging, and genetic testing. Recently, significant advancements have occurred in pharmacological and invasive therapies that are transforming the management of hypertrophic cardiomyopathy, including the introduction of cardiac myosin inhibitors, radiofrequency ablation, and gene editing. Additional trials are being conducted on investigational therapies, with the results anticipated in the near future. This review aims to provide a concise overview of both currently approved and investigational treatments for hypertrophic cardiomyopathy.

Indexed as

advanced therapieshypertrophic cardiomyopathyprocedural interventions

Identifiers

PMID40564046
PMCPMC12189642

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.