Evidence map›Paper›PMID 40564024›Full record

ArticleBiomedicines2025

Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer.

Gavin P Dowling, Aisling Hegarty, Gordon R Daly, Sandra Hembrecht, Cian M Hehir, Gavin G Calpin, Richard Hogan, David O'Reilly, Eithne Downey, Sinead Toomey and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Gavin P DowlingDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0002-2267-2022
Aisling HegartyDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Gordon R DalyDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Sandra HembrechtDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0001-5774-4500
Cian M HehirDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Gavin G CalpinDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0002-0266-2038
Richard HoganDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
David O'ReillyBeaumont RCSI Cancer Centre, Beaumont Hospital, D09 FT51 Dublin, Ireland.
Eithne DowneyBeaumont RCSI Cancer Centre, Beaumont Hospital, D09 FT51 Dublin, Ireland.
Sinead ToomeyMedical Oncology Laboratory, Department of Molecular Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Liam GroganBeaumont RCSI Cancer Centre, Beaumont Hospital, D09 FT51 Dublin, Ireland.
Oscar BreathnachBeaumont RCSI Cancer Centre, Beaumont Hospital, D09 FT51 Dublin, Ireland.
Michael AllenDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Patrick G MorrisBeaumont RCSI Cancer Centre, Beaumont Hospital, D09 FT51 Dublin, Ireland.
Colm PowerDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Leonie S YoungDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Arnold D K HillDepartment of Surgery, Royal College of Surgeons in Ireland, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.ORCID 0000-0001-9617-7983
Bryan T HennessyMedical Oncology Laboratory, Department of Molecular Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adjuvant therapybreast cancerbreast surgerytargeted therapytrastuzumab

Identifiers

PMID40564024
PMCPMC12189480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.