Evidence map›Paper›PMID 40563994›Full record

ArticleBiomedicines2025

A Promising Approach to Psoriasis Vulgaris Management with N-Acetylcysteine and Vitamin E: Targeting the Interplay of Inflammatory and Oxidative Stress.

Nira Elkalla, Manal H Elhamammsy, Nermeen Ibrahim Bedair, Ola Elazazy, Amal A El Kholy

Registry-linked trialAbstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07352306 (The Efficacy of Topical Diacerein Cream in Patients With Psoriasis Vulgaris), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07352306 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Efficacy of Topical Diacerein Cream in Patients With Psoriasis Vulgaris

TypeinterventionalSponsorCairo UniversityRan2026 to 2027Enrolled60ConditionsPsoriasis VulgarisArmsDiacerein, Placebo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nira ElkallaClinical Pharmacy Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt.
Manal H ElhamammsyClinical Pharmacy, Clinical Pharmacy Department, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
Nermeen Ibrahim BedairDermatology, Andrology, Sexual Medicine and STDs Department, Faculty of Medicine, Helwan University, Cairo 11795, Egypt.ORCID 0000-0003-0162-5080
Ola ElazazyBiochemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo 11829, Egypt.
Amal A El KholyClinical Pharmacy, Clinical Pharmacy Department, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.ORCID 0000-0003-4917-6392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IL-36γMDAN-acetylcysteinePASIpsoriasisvitamin E

Identifiers

PMID40563994
PMCPMC12189057

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.