Evidence map›Paper›PMID 40563983›Full record

ArticleBiology2025

Potential Role of Probiotic Strain

Gina Cavaliere, Egidia Costanzi, Beniamino Cenci-Goga, Marco Misuraca, Giovanna Traina

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Screening and Characterization ofFoods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gina CavaliereDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-5890-1002
Egidia CostanziDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Beniamino Cenci-GogaDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-3993-6258
Marco MisuracaDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Giovanna TrainaDepartment of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-9996-3584

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histamine intolerance is a condition that occurs when there is an imbalance between the accumulation and degradation of histamine within the body. Excess histamine is metabolized and then degraded by two enzymes, of which the most abundant is the vesicular diamine oxidase (DAO). An imbalance or a state of dysbiosis of the intestinal microbiota has been observed in patients with histamine intolerance compared to healthy individuals. Studies indicate that the administration of bifidobacteria or lactobacilli alone or in mixtures can alter colonic microbiota populations and metabolic activities. The present study has evaluated the ability of a probiotic bacterial strain to stimulate the release of cellular DAO from an in vitro model of the human intestinal epithelial barrier. The results indicate that, under the experimental conditions used, probiotic strain

Indexed as

diamine oxidase (DAO)histamine intoleranceHT29 cellsLactiplantibacillus plantarum LP115probiotics

Identifiers

PMID40563983
PMCPMC12189723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.