Evidence map›Paper›PMID 40563880›Full record

ReviewBiology2025

Probiotic-Vaccine Synergy in Fish Aquaculture: Exploring Microbiome-Immune Interactions for Enhanced Vaccine Efficacy.

Muhammad Tayyab, Waqar Islam, Waqas Waqas, Yueling Zhang

Abstract readReview
In one paragraph

Review in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Probiotics as Potential Enhancers of Veterinary Vaccines.Probiotics and antimicrobial proteins · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Evaluation of Immunoprotective Activities of White Button Mushroom (Animals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad TayyabGuangdong Provincial Key Laboratory of Marine Biology, Institute of Marine Sciences, Shantou University, Shantou 515063, China.ORCID 0000-0002-7826-5442
Waqar IslamXinjiang Key Laboratory of Desert Plant Roots Ecology and Vegetation Restoration, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China.ORCID 0000-0002-2383-402X
Waqas WaqasGuangdong Provincial Key Laboratory of Marine Biology, Institute of Marine Sciences, Shantou University, Shantou 515063, China.
Yueling ZhangGuangdong Provincial Key Laboratory of Marine Biology, Institute of Marine Sciences, Shantou University, Shantou 515063, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid expansion of aquaculture is vital for global food security, yet it faces persistent threats from disease outbreaks, vaccine inefficacy, and antibiotic overuse, all of which undermine sustainability. Conventional vaccines often fail to induce robust mucosal immunity, spurring interest in probiotics as adjuvants to enhance immunogenicity. Probiotics such as

Indexed as

antibiotic reductionaquacultureimmune primingmicrobiome modulationmucosal immunityone healthprobioticssustainable aquaculturesynbioticsvaccines

Identifiers

PMID40563880
PMCPMC12189079

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.