Evidence map›Paper›PMID 40563822›Full record

ArticleBrain sciences2025

How Cognitive Reserve Could Protect from Dementia? An Analysis of Everyday Activities and Social Behaviors During Lifespan.

Francesca Morganti, Ilia Negri

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francesca MorgantiDepartment of Human and Social Sciences, University of Bergamo, 24129 Bergamo, Italy.ORCID 0000-0002-2976-0244
Ilia NegriDepartment of Economy Statistic and Finance, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-8630-2362

Funding

Ministero dell'università e della ricerca 2022RAESSJ
6 · The paper itself

Abstract

BACKGROUND/

objectivesIn the last decade, there has been a notable increase in the prevalence of cognitive decline among the elderly population. This phenomenon is further compounded by the concurrent rise in life expectancy, indicating a growing concern for the health and well-being of individuals in this demographic. Dementia has become a disease with a strong social impact, not exclusively limited to its health dimension. It is generally accepted that lifestyle factors and psychological attitudes toward life challenges may serve as protective mechanisms against pathological cognitive decline. The objective of this contribution is to evaluate the impact of lifestyle factors (e.g., physical activity, employment history, nutrition, technology use, etc.), stressors (e.g., illness, rare events, abandonments, home moving, etc.), and sociability (e.g., marriage, active friend network, children proximity, work relationships, etc.) at the onset of pathological cognitive frailty.

methodsIn this study, a semi-structured interview was administered to 32 individuals over the age of 65 during their initial neuropsychological evaluation for suspected dementia.

resultsLinear regressions with Mini Mental State Examination scores indicated that lifestyle and sociability factors offer a degree of protection against cognitive decline, while stressors were found to be unrelated to this phenomenon.

conclusionsThe utilization of contemporary technologies, the possession of a driver's license, and the maintenance of an active social network have been demonstrated to possess a high degree of predictive value with respect to cognitive reserve in the context of aging.

Indexed as

cognitive reservedementia preventionfrailty in aginglifespan preventionlifestyle risk reductionsocial relationshipsstressors

Identifiers

PMID40563822
PMCPMC12190983

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.