Evidence map›Paper›PMID 40563758›Full record

ReviewBrain sciences2025

Neuroendoscopy and Postoperative Nausea and Vomiting: Pathophysiology, Incidence and Management Strategies.

Vincenzo Pota, Francesco Coletta, Francesca Pascazio, Pasquale Rinaldi, Antonio Tomasello, Giovanna Paola De Marco, Francesca Schettino, Maria Beatrice Passavanti, Pasquale Sansone, Maria Caterina Pace and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vincenzo PotaDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.ORCID 0000-0001-9999-3388
Francesco ColettaEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.ORCID 0000-0002-6864-6655
Francesca PascazioDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.
Pasquale RinaldiEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.ORCID 0009-0005-2088-6317
Antonio TomaselloEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.
Giovanna Paola De MarcoEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.ORCID 0000-0001-6581-6172
Francesca SchettinoEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.
Maria Beatrice PassavantiDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.ORCID 0000-0002-9659-0847
Pasquale SansoneDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.ORCID 0000-0003-0873-3586
Maria Caterina PaceDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.
Manlio BarbarisiMultidisciplinary Department of Medical-Surgical and Dental Specialities, University of Campania «L. Vanvitelli», 80138 Naples, Italy.ORCID 0000-0002-8161-6995
Roberto AltieriMultidisciplinary Department of Medical-Surgical and Dental Specialities, University of Campania «L. Vanvitelli», 80138 Naples, Italy.
Romolo VillaniEmergency Anesthesia, Burn Intensive Care Unit and Poison Control Center, AORN Antonio Cardarelli, 80131 Naples, Italy.ORCID 0000-0001-7572-0721
Francesco CoppolinoDepartment of Women, Child, General and Specialistic Surgery, University of Campania «L. Vanvitelli», 80138 Naples, Italy.ORCID 0000-0002-1362-7393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendoscopy is a minimally invasive surgical technique used to treat brain pathologies such as hydrocephalus, arachnoid cysts, and skull base tumors. While it offers several advantages, including reduced tissue trauma and lower morbidity, it is associated with a high risk of postoperative nausea and vomiting (PONV). This paper provides a narrative review of the literature on the incidence, pathophysiology, and management of PONV in patients undergoing neuroendoscopic procedures. The review includes several studies published between 2001 and 2024, analyzing specific risk factors such as female gender, postoperative opioid use, extended endoscopic approaches, and cavernous sinus dissection. PONV prevention strategies include a multimodal approach combining total intravenous anesthesia (TIVA) with propofol, perioperative hydration, and pharmacological prophylaxis (5-HT3 receptor antagonists, NK1 antagonists, dexamethasone, and droperidol). Despite advances in surgical and anesthetic techniques, further research is needed to develop procedure-specific protocols and optimize PONV management in neuroendoscopy.

Indexed as

antiemeticscraniotomyminimally invasive neurosurgeryneuroendoscopyPONVrisk factors

Identifiers

PMID40563758
PMCPMC12191331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.