Neutrophil to Lymphocyte Ratio as a Biomarker for the Prediction of Cancer Outcomes and Immune-Related Adverse Events in a CTLA-4-Treated Population.

Michael M Cunningham, Rachel Romero, Carolina Alvarez, Shruti Saxena Beem, Todd A Schwartz, Rumey C Ishizawar

Abstract read

In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael M CunninghamDivision of Rheumatology, Allergy, and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, NC 27514, USA.

Rachel RomeroAtrium Health Rheumatology, 200 Medical Park Drive, Suite 330, Concord, NC 28025, USA.

Carolina AlvarezThurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA.

Shruti Saxena BeemThurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0003-1827-1987

Todd A SchwartzThurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-0232-2543

Rumey C IshizawarDivision of Rheumatology, Allergy, and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, NC 27514, USA.ORCID 0000-0001-5952-7884

Funding

TARC 2019 Pilot Research Grant No grant number

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer biomarkercancer outcomesCTLA-4 blockadeimmune checkpoint inhibitorimmune-related adverse eventsimmunotherapyneutrophil to lymphocyte ratiopredictive modelingrheumatologic irAEs

Identifiers

PMID40563660

DOI10.3390/cancers17122011

PMCPMC12190284

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.