Evidence map›Paper›PMID 40563578›Full record

ReviewCancers2025

Updates on Liquid Biopsy and ctDNA in Transplant Oncology.

Abigail Loszko, Matthew M Byrne, Cristina Jimenez-Soto, Koji Tomiyama, Yuki Bekki, Roberto Hernandez-Alejandro

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abigail LoszkoDepartment of Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0009-0006-0173-194X
Matthew M ByrneDepartment of Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0001-5106-4424
Cristina Jimenez-SotoTransplant Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0003-2238-3076
Koji TomiyamaTransplant Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.
Yuki BekkiTransplant Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-2984-3277
Roberto Hernandez-AlejandroTransplant Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplant oncology is a rapidly evolving discipline that incorporates oncology, transplant medicine, and surgery. As the field continues to grow, there remains an opportunity to enhance patient selection, detect recurrence after liver transplantation, and optimize treatment after recurrence. Liquid biopsies are an emerging resource to improve patient care. In this review, we evaluate the most recent available data on circulating tumor DNA and how it pertains to primary and metastatic hepatobiliary malignancies. We discuss the opportunities and current limitations to clinical practice, especially in relation to total hepatectomy and liver transplantation. We conclude that as both transplant oncology and our understanding of circulating tumor DNA continue to evolve, rigorous, prospective study is required to integrate this technology into a clinical paradigm.

Indexed as

cholangiocarcinomacirculating tumor DNAcolorectal liver metastasisctDNAhepatobiliary malignancyhepatocellular carcinomaliquid biopsyliver transplantationnext-generation sequencingtransplant oncology

Identifiers

PMID40563578
PMCPMC12191371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.