Evidence map›Paper›PMID 40563568›Full record

ArticleCancers2025

Longitudinal Cohort Study of the Relationship Between Illness Perception, Perceived Social Support, and Psychosocial Quality of Life in Adolescents and Young Adults Newly Diagnosed with Cancer: Outcomes from a BRIGHTLIGHT Study.

Bethany Wickramasinghe, Lorna A Fern, Rachel M Taylor, Richard G Feltbower, BRIGHTLIGHT Study Group

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bethany WickramasingheDepartment of Targeted Intervention, University College London, London WC1E 6BT, UK.ORCID 0009-0002-3855-0625
Lorna A FernCancer Clinical Trials Unit, University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.ORCID 0000-0003-4821-8466
Rachel M TaylorDepartment of Targeted Intervention, University College London, London WC1E 6BT, UK.ORCID 0000-0002-0853-0925
Richard G FeltbowerLeeds Institute for Data Analytics, School of Medicine, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0002-1728-9408
BRIGHTLIGHT Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesSocial support can enhance psychosocial health-related quality of life (PSQOL) in adult cancer patients. Adolescents and young adults (AYAs) with cancer face unique psychosocial challenges that intersect with key developmental milestones. Theoretical models propose that illness perceptions and social support are key determinants of coping strategies and long-term health outcomes in this context. These may be especially salient for AYAs, for whom peer relationships and identity formation are central.

methodsWe explored how perceived social support and illness perceptions influence PSQOL over time in AYA cancer patients through a secondary analysis of the BRIGHTLIGHT longitudinal cohort study.

resultsBRIGHTLIGHT followed 830 young people aged 13-24 across five time points (6-36 months post-diagnosis). Multi-level modelling revealed that PSQOL improved over time but remained consistently lower in females (mean: 69.62, 95% CI: 70.69 to -68.55). Greater perceived support from friends was associated with poorer PSQOL (β: -0.77, 95% CI: -1.007 to -0.54) and linked to negative illness perceptions, longer hospital stays (β: 0.01, 95% CI: 0.00 to -0.02), longer diagnostic intervals (β: -0.009, 95% CI: -0.02 to -0.00), and poorer clinical communication (β: 0.52, 95% CI: 0.01 to -1.03). A patient interpretation exercise with BRIGHTLIGHT's Young Advisory Panel contextualized these findings.

conclusionsWhile peer support could promote normalcy, it could also intensify distress through emotional pressure or social isolation. Future research should address not only access to social support but its quality and relevance to AYAs' unique psychosocial needs.

Indexed as

adolescentBRIGHTLIGHTcancerillness perceptionpeer supportpsychosocial quality of lifesocial supportyoung adult

Identifiers

PMID40563568
PMCPMC12190661

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.