Evidence map›Paper›PMID 40563511›Full record

ArticleBiomolecules2025

Brianolide from

Chia-Chen Wang, Kang-Ling Wang, Yu-Jou Hsu, Chao-Hsien Sung, Mei-Jung Chen, Meng-Fang Huang, Ping-Jyun Sung, Chi-Feng Hung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chia-Chen WangSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Kang-Ling WangDivision of Metabolism and Endocrinology, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 32551, Taiwan.
Yu-Jou HsuPhD Program in Pharmaceutical Biotechnology, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Chao-Hsien SungPhD Program in Pharmaceutical Biotechnology, Fu Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0002-0461-2050
Mei-Jung ChenInstitute of Biomedical Engineering, School of Health and Medical Engineering, Ming Chuan University, Taoyuan 33300, Taiwan.
Meng-Fang HuangSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Ping-Jyun SungNational Museum of Marine Biology and Aquarium, Pingtung County 94450, Taiwan.ORCID 0000-0002-6644-9236
Chi-Feng HungSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0003-3478-5451

Funding

Cardinal Tien Hospital CTH112A-FJU-2234National Science and Technology Council in Taiwan 113-2320-B-030-007-MY3Taoyuan Armed Force General Hospital TYAFGH-A-113016
6 · The paper itself

Abstract

Atopic dermatitis (AD) is a common chronic skin disease affecting both children and adults. Currently lacking a clinical cure, AD presents significant physical and emotional challenges for patients and their families, substantially impacting their quality of life. This underscores significant unmet needs in AD management and highlights the necessity for developing effective therapeutic applications. Recently, several chlorine-containing active substances with promising pharmacological activity have been discovered in soft corals cultivated through coral farming. Among these, brianolide, isolated from the soft coral

Indexed as

AnthozoaDermatitis, AtopicMAP Kinase Signaling SystemNF-kappa BAnimalsCell LineCytokinesDinitrochlorobenzeneDisease Models, AnimalHaCaT CellsHumansKeratinocytesMiceSkinCytokinesDinitrochlorobenzeneNF-kappa Batopic dermatitisbrianolideBriareum stecheiinflammatorysoft coral

Identifiers

PMID40563511
PMCPMC12190504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.