Role of CORO1A in Regulating Immune Homeostasis of Mammary Glands and Its Contribution to Clinical Mastitis Development in Dairy Cows.

Bohao Zhang, Na Chen, Xing Yu, Jianfu Li, Weitao Dong, Yong Zhang, Xingxu Zhao, Quanwei Zhang

Abstract read

In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bohao ZhangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.ORCID 0000-0003-1064-7222

Na ChenCollege of Life Science and Technology, Gansu Agriculture University, Lanzhou 730070, China.ORCID 0009-0000-9369-3034

Xing YuCollege of Life Science and Technology, Gansu Agriculture University, Lanzhou 730070, China.

Jianfu LiCollege of Life Science and Technology, Gansu Agriculture University, Lanzhou 730070, China.

Weitao DongCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.

Yong ZhangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.

Xingxu ZhaoCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.ORCID 0000-0002-5470-3815

Quanwei ZhangCollege of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.ORCID 0000-0002-5476-508X

Funding

Education-industrial support plan of the Gansu Provincial Department 2024CYZC-30Excellent Doctoral Project of Science, and Technology Plan Funding of Gansu Province 24JRRA676National Natural Science Foundation of China U21A20262

6 · The paper itself

Abstract

Immune homeostasis refers to the immune system's ability to maintain a dynamic balance, defend against infections while preventing excessive inflammation, and preserve normal physiological activity. However, its regulatory role in the mammary glands (MGs) of cows with clinical mastitis (CM) remains unclear. This study examined MG tissue samples collected from healthy Holstein cows and those with CM caused by

Indexed as

HomeostasisMammary Glands, AnimalMastitis, BovineMicrofilament ProteinsStaphylococcal InfectionsAnimalsCattleFemaleMacrophagesStaphylococcus aureusToll-Like Receptor 2coronin proteinsMicrofilament ProteinsToll-Like Receptor 2bioinformatics analysisclinical mastitiscoronin1Aimmune homeostasis

Identifiers

PMID40563467

DOI10.3390/biom15060827

PMCPMC12191025

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.