Evidence map›Paper›PMID 40563416›Full record

ArticleBiomolecules2025

The Association of

Adam Kamiński, Mateusz Gutowski, Anna Bogacz, Marta Podralska, Izabela Uzar, Michał Soczawa, Maciej Brązert, Bogusław Czerny

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam KamińskiDepartment of Children Orthopedics and Musculosceletal Oncology, Pomeranian Medical University in Szczecin, UniiLubelskiej 1, 71-252 Szczecin, Poland.
Mateusz GutowskiDepartment of Anaesthesiology and Intensive Care, Pomeranian Medical University in Szczecin, UniiLubelskiej 1, 71-252 Szczecin, Poland.
Anna BogaczDepartment of Physiology, Poznan University of Medical Sciences, Smoluchowskiego 11, 60-179 Poznan, Poland.ORCID 0000-0001-5455-8315
Marta PodralskaDepartment of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Plewiska, Poland.
Izabela UzarDepartment of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, 71-230 Szczecin, Poland.
Michał SoczawaDepartment and Clinic of Urology and Urological Oncology, Pomeranian Medical University in Szczecin, al. PowstańcówWielkopolskch 72, 70-111 Szczecin, Poland.
Maciej BrązertDepartmentof Infertility Diagnostics and Treatment, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Bogusław CzernyDepartment of Stem Cells and Regenerative Medicine, Institute of Natural Fibres and Medicinal Plants, Kolejowa 2, 62-064 Plewiska, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is a chronic metabolic condition characterized by progressive loss of bone mass and disruption of the bone spatial architecture. Pathological changes are influenced by multiple factors, including genetic predispositions. Identifying risk factors for osteoporosis is crucial for recognizing at-risk populations, implementing preventive strategies, and supporting diagnostics. Type I collagen, composed of two chains-α1(I) and α2(I), encoded by the

methodsThe study included 570 unrelated women: 119 diagnosed with osteoporosis, 96 with osteopenia, and 355 healthy controls. Polymorphisms in the

resultsThe results showed no significant differences in the distribution of genotypes and alleles of rs412777 between the groups. However, the rs17166249 T allele was found to be more prevalent in the osteoporosis group, although the association was not statistically significant after adjusting for confounders. Furthermore, no significant correlations were observed between the genotypes of either SNP and BMD parameters such as T-score, Z-score, and BMD measurements.

conclusionThese findings suggest that while the

Indexed as

Bone DensityCollagen Type IOsteoporosis, PostmenopausalPolymorphism, Single NucleotidePostmenopauseAgedAllelesBone Diseases, MetabolicCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMiddle AgedPolandCOL1A2 protein, humanCollagen Type Ibone mineral densityCOL1A2osteoporosispolymorphismreal-time PCR

Identifiers

PMID40563416
PMCPMC12190609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.