Evidence map›Paper›PMID 40563408›Full record

ArticleBiomolecules2025

Transcript PHF19-207 as a Potential Biomarker for Colon Cancer Diagnosis and Screening.

Stefan Kmezic, Sandra Dragicevic, Tamara Babic, Jelena Ljubicic, Ivan Dimitrijevic, Aleksandra Nikolic, Velimir Markovic

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefan KmezicClinic for Digestive Surgery, University Clinical Center of Serbia, dr Koste Todorovica 6, 11 000 Belgrade, Serbia.ORCID 0000-0003-2047-5524
Sandra DragicevicGene Regulation in Cancer Group, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11 042 Belgrade, Serbia.ORCID 0000-0002-1602-1880
Tamara BabicGene Regulation in Cancer Group, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11 042 Belgrade, Serbia.
Jelena LjubicicClinic for Allergy and Immunology, University Clinical Center of Serbia, dr Koste Todorovica 2, 11 000 Belgrade, Serbia.ORCID 0009-0001-6471-2037
Ivan DimitrijevicClinic for Digestive Surgery, University Clinical Center of Serbia, dr Koste Todorovica 6, 11 000 Belgrade, Serbia.
Aleksandra NikolicGene Regulation in Cancer Group, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11 042 Belgrade, Serbia.ORCID 0000-0003-3420-3896
Velimir MarkovicClinic for Digestive Surgery, University Clinical Center of Serbia, dr Koste Todorovica 6, 11 000 Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent comprehensive pan-cancer study indicated the high translational potential of the transcript PHF19-207 as a biomarker for colon cancer. This study aimed to analyze the expression of PHF19-207 in colon tissue samples from two different settings to evaluate its clinical utility for diagnosis and screening. Surgical samples of colon tumor and non-tumor tissue were analyzed to determine the diagnostic value of PHF19-207 and its potential correlation with tumor characteristics. Additionally, biopsied samples from individuals undergoing national colorectal cancer screening were examined to assess the potential use of PHF19-207 in early detection. PHF19-207 expression levels were measured in all samples using Real-Time Polymerase Chain Reaction. A statistically significant difference was observed between tumor and non-tumor tissue (

Indexed as

Biomarkers, TumorColonic NeoplasmsDNA-Binding ProteinsTranscription FactorsAdultAgedEarly Detection of CancerFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedROC CurveBiomarkers, TumorDNA-Binding ProteinsTranscription Factorscancer diagnosiscancer screeningcolon cancergene expressionPHF19transcript

Identifiers

PMID40563408
PMCPMC12191053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.