Evidence map›Paper›PMID 40563301›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Recovery from Resistance Exercise with or Without Blood Flow Restriction Results in an Early Biphasic Pattern of Change in Albumin Cys34 Oxidation in Untrained Males.

Zi Xiang Lim, Jackson Peos, Stefan Ostojic, Peter G Arthur, Paul A Fournier

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zi Xiang LimExercise Physiology and Biomarkers Laboratory, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456, Singapore.ORCID 0000-0002-0562-9321
Jackson PeosSchool of Human Sciences, Department of Sport Science, Exercise & Health, The University of Western Australia, Perth 6009, Australia.
Stefan OstojicSchool of Human Sciences, Department of Sport Science, Exercise & Health, The University of Western Australia, Perth 6009, Australia.
Peter G ArthurSchool of Molecular Sciences, The University of Western Australia, Perth 6009, Australia.ORCID 0000-0002-1257-8200
Paul A FournierSchool of Human Sciences, Department of Sport Science, Exercise & Health, The University of Western Australia, Perth 6009, Australia.

Funding

Australian Government International Research Training Programme Scholarship NA
6 · The paper itself

Abstract

backgroundOxidative stress contributes to the activation of muscle protein synthesis after high-intensity resistance exercise (HIRE) or low-intensity resistance exercise combined with blood flow restriction (LIBFR), but it is unclear if this oxidative stress response post-exercise is monophasic or multiphasic. We aimed to answer this question using albumin Cys34 oxidation as an oxidative stress marker.

methodsSeven untrained individuals completed HIRE and LIBFR on separate days. Albumin Cys34 oxidation (total and reversibly and irreversibly oxidized fractions), muscle oxygenation, oxygen consumption (V˙O2), lactate, and heart rate (HR) were measured before and up to 5 h post-exercise.

resultsBoth HIRE and LIBFR induced a biphasic increase in total oxidized albumin Cys34, with a transient peak in irreversibly oxidized albumin Cys34 immediately post-exercise (

conclusionHere, we show that resistance exercise, with or without blood flow restriction, results in an early biphasic oxidative stress response after exercise.

Indexed as

antioxidantlow-intensity resistance exercise combined with blood flow restrictionmaleimide labelingprotein thiol oxidationreactive oxygen and nitrogen species

Identifiers

PMID40563301
PMCPMC12189344

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