Evidence map›Paper›PMID 40563258›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Multi-Omics Analysis of Chronic Heat Stress-Induced Biological Effects, Liver Injury, and Heat Tolerance Mechanisms via Oxidative and Anti-Inflammatory Pathways in Early-Pregnancy Sows.

Jie Chai, Zhenhao Wen, Li Chen, Qiang Pu, Taorun Luo, Xiaoqian Wu, Zihan Ma, Zonggang Luo, Jia Luo, Jingyong Wang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jie ChaiChongqing Academy of Animal Sciences, Chongqing 402460, China.
Zhenhao WenCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.ORCID 0009-0003-3029-023X
Li ChenChongqing Academy of Animal Sciences, Chongqing 402460, China.
Qiang PuCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Taorun LuoCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Xiaoqian WuCollege of Food Science, Southwest University, Chongqing 400715, China.
Zihan MaCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Zonggang LuoCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Jia LuoCollege of Animal Science and Technology, Southwest University, Chongqing 400715, China.ORCID 0000-0002-1582-5174
Jingyong WangChongqing Academy of Animal Sciences, Chongqing 402460, China.

Funding

the earmarked fund CARS-35the National Key Research and Development Program 2021YFD1301101the Strategic Cooperation Funding Project between Chongqing Municipal Government and chinese Academy of Agriculturel Sciences 23310
6 · The paper itself

Abstract

The prenatal environment critically influences sow and offspring health, with the liver being highly susceptible to heat stress (HS) and vital for antioxidant defense. However, mechanisms underlying HS impacts on early pregnancy and hepatic adaptation remain unclear. This study applied multi-omics to analyze chronic HS responses in early-pregnancy sows. Results demonstrated that HS reduced blood oxygen (PO

Indexed as

heat stressliveroxidative stresspregnantsow

Identifiers

PMID40563258
PMCPMC12189682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.