Evidence map›Paper›PMID 40563257›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Effects of Mogroside V on Quality and Antioxidant Activity of Boar Frozen-Thawed Sperm.

Heming Sui, Xin Wang, Kunlong Hu, Xiaoyu Zuo, Haonan Li, Zhengyu Diao, Jiajing Feng, Yunhai Zhang, Zubing Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Heming SuiAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xin WangAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Kunlong HuAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xiaoyu ZuoAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Haonan LiAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhengyu DiaoAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Jiajing FengAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Yunhai ZhangAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.ORCID 0000-0001-9721-5910
Zubing CaoAnhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.ORCID 0000-0002-8916-8154

Funding

and the Anhui Provincial Innovation and Entrepreneurship Training Plan for Undergraduate Student S202310364068the Anhui Provincial Innovation and Entrepreneurship Support Plan for Returnee Scholar 2020LCX015the Joint Research Project on the Anhui Local Pigs Breeding and Utilization 340000211260001000431the Special Fund for Anhui Agriculture Research System AHCYJSTX-04
6 · The paper itself

Abstract

Cryopreserved pig semen tends to produce excessive reactive oxygen species (ROS) during the thawing process, which leads to a decline in semen quality during in vitro storage. Mogroside V (MV) has been proven to be an effective antioxidant, and previous research has shown that MV can delay oocyte aging and improve the in vitro maturation efficiency of pig oocytes. However, the role of MV in the cryopreservation capacity of animal sperm remains unclear. To evaluate the effect of MV on sperm motility after thawing, different concentrations of MV (0, 25, 50, 75, 100 μmol/L) were added to the thawing medium. By comparing the sperm motility and kinematic parameters in the thawing medium with different MV concentrations and incubation times (0, 1, 2, and 4 h), we ultimately selected sperm thawed immediately in the medium supplemented with 75 μmol/L MV for subsequent experiments. Compared with the control group, the sperm thawing medium containing MV improved sperm quality during the freeze-thaw process. Immediate evaluation after thawing at 37 °C showed that supplementation with 75 μmol/L MV produced an optimal effect on the maintenance of motility, plasma membrane integrity, the acrosome integrity, the ROS levels, and the T-AOC activity. In conclusion, MV supplementation improves the quality of frozen-thawed sperm by enhancing sperm function and preventing oxidative stress.

Indexed as

antioxidantcryopreservationfrozen–thawed semenoxidative stresssperm quality

Identifiers

PMID40563257
PMCPMC12189451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.