ArticleHuman genomics2025
Pharmacists' perspectives on integrating pharmacogenetics in clinical practice.
Article in Human genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study.The pharmacogenomics journal · 2026Article
- From evidence to implementation: key priorities for pharmacogenomics-guided treatment and prevention from a European expert workshop.European journal of human genetics : EJHG · 2026Article
- Barriers, facilitators, and implementation strategies for pharmacogenomics in community pharmacies: a cross-sectional survey among local champions in pharmacies and key opinion leaders in pharmacogenomics.International journal of clinical pharmacy · 2026Article
- The critical need to implement pharmacogenomics in public health services: Mexico in the global picture.Frontiers in public health · 2026Article
- Pharmacogenomics knowledge and implementation readiness among community pharmacists in Jordan: A national cross-sectional study.PloS one · 2026Article
- Integrating genetic insights into pain management and opioid use optimization in chronic pain and substance abuse populations.Exploratory research in clinical and social pharmacy · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
introductionThe successful implementation of pharmacogenetics (PGx) in many developed countries has significantly enhanced personalized care and improved both clinical and financial outcomes. This study was designed to evaluate the current knowledge, prevailing attitudes, and perceived ability of pharmacists to actively participate in the integration of PGx into their practice settings.
methodsA cross-sectional study was conducted among pharmacists in Yemen using convenience sampling. Data was collected through an online-based questionnaire using the Google Forms platform. Both descriptive and inferential analyses were employed.
resultsWith a total of 211 participants involved. Most participants held a bachelor's degree in pharmacy (45%, n = 95). Approximately 70% of respondents reported having between one and five years of experience in pharmacy practice. About three-quarters of pharmacists showed high knowledge score regarding PGx (74.4%; 95% CI: 68.47 - 80.34), with overall pharmacists' knowledge score had a median and IQR of 4( 3-5). The score of knowledge exhibited statistical significance in relation to participants' years of professional experience (p = 0.005). Overall, pharmacists expressed positive attitudes toward PGx. The top two challenges reported for the adoption of PGx in practice were "high cost" and "limited availability of tests". Additionally, about 70% agreed that they lacked knowledge about the specific PGx tests required.
conclusionPharmacists exhibit promising attitudes towards PGx. Nevertheless, there is a clear need to reinforce their foundational knowledge and enhance their confidence in the practical application of PGx principles. Effective integration of personalized medicine will necessitate collaborative efforts among key stakeholders, including the Ministry of Health, academic institutions, and professional pharmacy associations.
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