Evidence map›Paper›PMID 40562936›Full record

ArticleNature2025

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase.

Nitin Kapadia, Paul Nurse

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Decoding Cdk1 control: from mitotic thresholds to meiotic specificity.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nitin KapadiaCell Cycle Laboratory, The Francis Crick Institute, London, UK. nitin.kapadia@crick.ac.uk.ORCID 0000-0003-4514-7631
Paul NurseCell Cycle Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-9244-7787

Funding

UK Medical Research CouncilWellcome Trust CC2003
6 · The paper itself

Abstract

Mitotic onset is a critical transition for eukaryotic cell proliferation. The commonly held view of mitotic control is that the master regulator, cyclin-dependent kinase (CDK), is first activated in the cytoplasm, at the centrosome, initiating mitosis

Indexed as

Cyclin-Dependent KinasesMitosisSchizosaccharomycesSpatio-Temporal AnalysisCell NucleusCentrosomeCyclinsCytoplasmDNA DamageDNA ReplicationEnzyme ActivationSchizosaccharomyces pombe ProteinsCyclin-Dependent KinasesCyclinsSchizosaccharomyces pombe Proteins

Identifiers

PMID40562936
PMCPMC12310531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.