Evidence map›Paper›PMID 40562881›Full record

Trial reportJournal of general internal medicine2026

Racial Disparities in Unmet Pain Treatment Preference, Pain Treatment Satisfaction and Subsequent Opioid Misuse: A Secondary Analysis of a National Multisite RCT.

Max Jordan Nguemeni Tiako, Eden Engel-Rebitzer, Ari Friedman, Frances Shofer, Abby Dolan, Erik P Hess, Jeanmarie Perrone, Marilyn M Schapira, Zachary F Meisel

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Role of Satisfaction, Trust, and Shared Decision-Making in Opioid Misuse Risk After Unmet Analgesic Preferences for Acute Pain.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Max Jordan Nguemeni TiakoDivision of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. mnguemeni@mednet.ucla.edu.ORCID 0000-0002-5468-8926
Eden Engel-RebitzerDepartment of Medicine, Brigham & Women's Hospital, Boston, MA, USA.
Ari FriedmanDepartment of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Frances ShoferDepartment of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Abby DolanDepartment of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Erik P HessDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jeanmarie PerroneDepartment of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Marilyn M SchapiraDivision of General Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Zachary F MeiselDepartment of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Funding

Patient-Centered Outcomes Research Institute CDR-1511-33496
6 · The paper itself

Abstract

backgroundRacial disparities in opioid prescriptions for pain are well documented. Evidence shows undertreated acute pain increases the risk of developing chronic pain, which puts patients at risk of long-term opioid use and misuse. We sought to determine the association between satisfaction with analgesia, unmet opioid preference, and opioid misuse risk by race in a diverse, longitudinal cohort.

methodsWe conducted a secondary analysis of participants with complete data in an RCT of 1301 patients who presented to the emergency department (E.D.) for acute kidney or back pain. Our primary outcome was opioid misuse risk quantified by the current opioid misuse measure (COMM), a self-report 17-item measure of risk of aberrant medication-related behavior among persons prescribed opioids for chronic pain, measured 90 days after the index E.D. visit. We used descriptive statistics and linear regressions to determine associations between satisfaction with analgesia (1-10, measured 1-day post-visit), unmet opioid preference, and opioid misuse risk by race, adjusting for age and sex.

resultsWe analyzed 735 participants. The mean (SD) age was 39.6 (13.6), 58.9% (n = 432) were female, 46.4%(n = 341) were White, and 36.9%(n = 271) were Black. Unmet preference was more common among Black (21.8%, n = 59) vs. White (15%, n = 51) participants. Black (vs White) participants had a higher median (IQR) COMM (4 (1 - 12) vs 3 (1 - 6), P < 0.001, and lower median satisfaction (7 (4-10) vs 8 (5 - 10), P = 0.002). Adjusting for unmet preference and satisfaction, Black (vs. White) participants had higher COMM (β = 3.4, 95% CI 1.6-5.3, P = 0.01). Unmet preference was associated with higher COMM (β = 2.3, 95% CI 1.3-3.2, P < 0.001). Satisfaction was associated with lower COMM (β = - 0.5 pp, 95% CI - 0.7, - 0.2, P < 0.01). In a model with a triple interaction between satisfaction, unmet preference, and race, satisfaction was associated with lower COMM (- 0.3 pp, 95% CI - 0.5, - 0.1, P = 0.03) and mitigated the effect of unmet preference on Black participants' COMM (marginal effect β = - 1.3 pp, 95% CI - 1.9, - 0.7, P = 0.01).

conclusionSatisfaction with analgesia was protective against opioid misuse risk, especially among Black participants whose opioid preference was unmet. Addressing unmet preferences and understanding factors that shape patient satisfaction with analgesia could help reduce racial disparities in opioid misuse.

Indexed as

Analgesics, OpioidHealthcare DisparitiesOpioid-Related DisordersPain ManagementPatient PreferencePatient SatisfactionAdultBlack or African AmericanFemaleHumansLongitudinal StudiesMaleMiddle AgedUnited StatesWhiteAnalgesics, Opioidacute painCOMMemergency departmentopioidopioid misuseopioid overdose epidemicracial disparitiesunmet preference

Identifiers

PMID40562881
PMCPMC13009308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.