ReviewOncogene2025
Post-transcriptional control of gene expression by β-catenin: expanding the non-canonical ARMoury.
Review in Oncogene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- TOE1 is a β-catenin interacting protein regulating the proliferation of hematopoietic cells through PAK2 modulation.Stem cell reports · 2026Article
- RNA-based therapies for colorectal cancer: targeting the β-catenin pathway via microbiota -modulated miRNAs.Frontiers in molecular biosciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The Wnt/β-catenin pathway is an evolutionarily conserved signal transduction cascade with critical regulatory roles in cellular proliferation, cell fate determination and tissue homeostasis. Through the regulation of multiple human stem cell systems, canonical Wnt signalling is not only a major contributor to normal development, but also heavily implicated in a multitude of human diseases, including cancer. The central mediator of the pathway β-catenin, first identified as Armadillo (ARM) in Drosophila, has well-defined roles in cell adhesion and transcription within the pathway. However, accumulating evidence suggests β-catenin functionality is more complex than initially anticipated with reported roles beyond those historically characterised, including the regulation of RNA and RNA-binding proteins (RBP). This review will summarise the current understanding around β-catenin as a post-transcriptional regulator in normal and malignant development, drawing particular attention to cell types not traditionally used to characterise Wnt signalling but uniquely placed to reveal novel β-catenin function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.