Evidence map›Paper›PMID 40562803›Full record

ArticleScientific reports2025

Association of height, BMI, and smoking status with prostate cancer risk before and after the introduction of PSA testing in Sweden.

Innocent B Mboya, Josef Fritz, Pietro Scilipoti, Christel Häggström, Marisa da Silva, Ming Sun, Jens Wahlström, Viktor Oskarsson, Karl Michaëlsson, Jerzy Leppert and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Innocent B MboyaDepartment of Translational Medicine, Lund University, Malmö, Sweden. ib.mboya@gmail.com.
Josef FritzDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Pietro ScilipotiDivision of Experimental Oncology/Unit of Urology, URI Institution, IRCCS San Raffaele Hospital, Milan, Italy.
Christel HäggströmDepartment of Diagnostics and Intervention, Northern Registry Centre, Umeå University, Umeå, Sweden.
Marisa da SilvaDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Ming SunDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Jens WahlströmDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Viktor OskarssonDepartment of Public Health and Clinical Medicine, Piteå Research Unit, Umeå University, Piteå, Sweden.
Karl MichaëlssonMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Jerzy LeppertCenter for Clinical Research, Region Västmanland, Uppsala University, Uppsala, Sweden.
Abbas ChabokCenter for Clinical Research, Region Västmanland, Uppsala University, Uppsala, Sweden.
Patrik K E MagnussonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Ylva Trolle LagerrosDivision of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden.
Stephanie E BonnDivision of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden.
Linnea HedmanDepartment of Public Health and Clinical Medicine, The OLIN Unit, Umeå University, Umeå, Sweden.
Pär StattinDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Tanja StocksDepartment of Translational Medicine, Lund University, Malmö, Sweden. tanja.stocks@med.lu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) incidence has steadily increased in Sweden, more steeply in the mid-1990s caused by increased opportunistic prostate-specific antigen (PSA) testing. Tallness, normal weight, and non-smoking are associated with more PSA testing, which increases detection of low-risk and localised PCa. We investigated time trends of height, body mass index (BMI), and smoking with PCa risk in 171,889 men in Sweden aged 50-64 years at baseline, who were linked to nationwide cancer registers during follow-up. Cox regression determined the association of these factors assessed before 1980, 1980-1994, and 1995-2004 with PCa risk. During 15 follow-up years, 8,049 men were diagnosed with PCa. The association of height with PCa was weakly positive across all calendar periods. For obesity (BMI ≥30 kg/m

Indexed as

Body HeightBody Mass IndexProstate-Specific AntigenProstatic NeoplasmsSmokingHumansIncidenceMaleMiddle AgedObesityRegistriesRisk FactorsSwedenProstate-Specific AntigenBody heightBody mass indexProstate-specific antigenProstatic neoplasms.Smoking

Identifiers

PMID40562803
PMCPMC12198391

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.