Evidence map›Paper›PMID 40562794›Full record

ArticleScientific reports2025

Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock.

Henrik Rundgren, Johan Sjöholm, Sanja Juric, Pellina Janson, Joline Kolerud, Robert Wallin, Paul Skorup, Miklos Lipcsey, Mattias Günther

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Henrik RundgrenSangair AB, Stockholm, Sweden.
Johan SjöholmSangair AB, Stockholm, Sweden.
Sanja JuricRISE Research Institutes of Sweden, Stockholm, Sweden.
Pellina JansonKarolinska Experimental Research and Imaging Centre (KERIC), Stockholm, Sweden.
Joline KolerudKarolinska Experimental Research and Imaging Centre (KERIC), Stockholm, Sweden.
Robert WallinSciEd Solutions, Stockholm, Sweden.
Paul SkorupDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Miklos LipcseyDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Mattias GüntherSection for Experimental Traumatology, Department of Neuroscience, Karolinska Institutet, Biomedicum - 8B, 171 77, Stockholm, Sweden. mattias.gunther@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is associated with substantial mortality rates. Traditional treatment strategies often fail to address the underlying dysregulation in immune response, necessitating novel therapeutic approaches. Ozone (O

Indexed as

ImmunomodulationOzonePseudomonas aeruginosaPseudomonas InfectionsShock, SepticAnimalsCytokinesDisease Models, AnimalSwineCytokinesOzoneAntibiotic resistanceIntensive careOzonePorcine sepsis modelPseudomonas aeruginosa

Identifiers

PMID40562794
PMCPMC12198400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.