Evidence map›Paper›PMID 40562731›Full record

ArticleEmerging infectious diseases2025

Disseminated Histoplasmosis in Persons Living with HIV, France and Overseas Territories,1992-2021.

Mathieu Nacher, Esaïe Marshall, Firouze Bani-Sadr, Sandrine Peugny, Blandine Denis, Elise Ouedraogo, Sebastien Gallien, Agnes Meybeck, Ugo Françoise, Antoine Adenis and 4 more

Abstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Predictors of mortality in hospitalized patients with disseminated histoplasmosis.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mathieu Nacher
Esaïe Marshall
Firouze Bani-Sadr
Sandrine Peugny
Blandine Denis
Elise Ouedraogo
Sebastien Gallien
Agnes Meybeck
Ugo Françoise
Antoine Adenis
Nicolas Vignier
Pierre Couppié
Pierre Sellier
Sophie Grabar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated histoplasmosis is a major issue among persons with advanced HIV in the Americas; it might also affect persons in sub-Saharan Africa, the Caribbean, and Asia and can be mistaken for other infections. By using 1992-2021 data from the French hospital database on HIV, we analyzed 198,798 persons with HIV follow-up in France and its overseas territories, identifying 553 (2.8/1,000 person-years) first episodes of disseminated histoplasmosis. Incidence rates varied by site of follow-up: 9.41 in French Guiana, 0.76 in Guadeloupe, 0.62 in Martinique, and 0.079 in mainland France. Incidence rates in France also varied between regions of origin or travel: 4.73 for Central or South America, 1.36 for the Caribbean, and 0.19 for sub-Saharan Africa or Asia. Differences persisted after adjusting for age, sex, CD4 count, and viral load at baseline. Overall, incidence and early death have declined, likely because of antiretroviral drug rollout in France.

Indexed as

AIDS-Related Opportunistic InfectionsHistoplasmosisHIV InfectionsAdultFemaleFranceFrench GuianaHistory, 21st CenturyHumansIncidenceMaleMartiniqueMiddle AgedAfricaAmericasAsiaCaribbeanFrancefungal infectionfungiglobal burdenHistoplasma spp.histoplasmosisHIV/AIDS and other retrovirusesincidence

Identifiers

PMID40562731
PMCPMC12205452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.