Evidence map›Paper›PMID 40562405›Full record

ReviewThe Journal of international medical research2025

Beyond barriers: The role of preexposure prophylaxis in the prevention of human immunodeficiency virus in women.

Alex Dang, Hillary Debs, Johnny Ruiz, Amber Vu, Melissa E Badowski

Abstract readReview
In one paragraph

Review in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alex DangUniversity of Illinois Chicago, Retzky College of Pharmacy, USA.
Hillary DebsUniversity of Illinois Chicago, Retzky College of Pharmacy, USA.
Johnny RuizUniversity of Illinois Chicago, Retzky College of Pharmacy, USA.
Amber VuUniversity of Illinois Chicago, Retzky College of Pharmacy, USA.
Melissa E BadowskiUniversity of Illinois Chicago, Retzky College of Pharmacy, USA.ORCID 0000-0001-7564-0131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preventive measures for human immunodeficiency virus infection have greatly evolved with the approval of preexposure prophylaxis. Despite their effectiveness, a significant gap exists in the initiation and adherence to these preventive measures among cisgender women. This review aims to highlight available implementation models to increase preexposure prophylaxis use and adherence in this population. A narrative review was conducted to identify studies focusing on preexposure prophylaxis use among cisgender women. Ultimately, 15 studies were included and categorized based on their intervention type: behavioral, health clinic, community, pharmacy, technology, or mobile. This review identified several intervention models that improved preexposure prophylaxis use and adherence among cisgender women. Behavioral interventions, such as preexposure prophylaxis-trained nurses and combined counseling with short message service reminders, significantly improved adherence. Health clinic-based interventions demonstrated the importance of regular follow-up and the potential for improved adherence through injectable preexposure prophylaxis. Community interventions highlighted the effectiveness of referral systems and technology-driven approaches, including mHealth interventions and real-time electronic adherence monitoring, to promote preexposure prophylaxis uptake and adherence. Implementing diverse interventions may considerably improve adherence and reduce the human immunodeficiency virus transmission rates in this population.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisFemaleHumansMedication AdherenceAnti-HIV Agentsantiretroviralhuman immunodeficiency virusPreexposure prophylaxispreventionwomen

Identifiers

PMID40562405
PMCPMC12198503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.