Evidence map›Paper›PMID 40562244›Full record

ArticleBioresource technology2025

Investigating anaerobic digestion microbiome resilience to high PFOA and PFOS mixtures during cometabolism.

Bianca F Costa, Christelle Sawaya, Jean Van Buren, Adam L Smith

Abstract read
In one paragraph

Article in Bioresource technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bianca F CostaAstani Department of Civil and Environmental Engineering, University of Southern California, 920 Downey Way, Los Angeles, CA 90089, USA.
Christelle SawayaAstani Department of Civil and Environmental Engineering, University of Southern California, 920 Downey Way, Los Angeles, CA 90089, USA.
Jean Van BurenAstani Department of Civil and Environmental Engineering, University of Southern California, 920 Downey Way, Los Angeles, CA 90089, USA.
Adam L SmithAstani Department of Civil and Environmental Engineering, University of Southern California, 920 Downey Way, Los Angeles, CA 90089, USA. Electronic address: smithada@usc.edu.

Funding

Southern California Superfund Research and Training Program for PFAS Assessment, Remediation, and Prevention (ShARP)P42ES036506 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Tun (Max) M Aung · 2025 to 2026
$8.2M
NIEHS NIH HHS P42 ES036506
6 · The paper itself

Abstract

Anaerobic digestion (AD) is a reducing environment with high microbial diversity and potential for biotransformation of PFAS. Yet, their fate and impact on the microbial community remains poorly understood. This study evaluated the long-term impact (100 d) of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) spiked at10 mg/L (low) and 100 mg/L (high), respectively. Although resilient to complete system failure, high PFAS concentrations disrupted AD, evidenced by 25-50 % reduction in methane content, 45 -48 % reduction in cumulative biogas production, and accumulation of butyric acid. No significant decrease in PFAS concentration was observed in the liquid fraction after 100 d relative to the kill controls, indicating PFAS adsorption behavior. However, PFAS concentrations were temporally variable. Microbial community analysis revealed enrichment of notable AD groups, such as Firmicutes, Synergistetes, and Methanomassillicoccus phyla in high PFAS reactors, which underscores the potential for the microbiome adaptation and informs future strategies for PFAS-contaminated sludge treatment.

Indexed as

Alkanesulfonic AcidsCaprylatesFluorocarbonsMicrobiotaAnaerobiosisBiodegradation, EnvironmentalBiofuelsBioreactorsMethaneSewageAlkanesulfonic AcidsBiofuelsCaprylatesFluorocarbonsMethaneperfluorooctane sulfonic acidperfluorooctanoic acidSewageCometabolismInhibitionMicrobial ecologyPFAS

Identifiers

PMID40562244
PMCPMC12649820

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.