Evidence map›Paper›PMID 40561644›Full record

ArticleWorld neurosurgery2025

Bioactive Therapies for Degenerative Disc Disease: Challenges and Innovations.

Alikhan B Fidai, Ashley Cardenas, Chibuikem A Ikwuegbuenyi, Anthony Robayo, Noah Willett, Ibrahim Hussain, Roger Härtl, Lawrence J Bonassar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alikhan B FidaiMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
Ashley CardenasMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA.
Chibuikem A IkwuegbuenyiDepartment of Neurological Surgery, Och Spine at New York Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.
Anthony RobayoDepartment of Neurological Surgery, Och Spine at New York Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.
Noah WillettDepartment of Neurological Surgery, Och Spine at New York Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.
Ibrahim HussainDepartment of Neurological Surgery, Och Spine at New York Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.
Roger HärtlDepartment of Neurological Surgery, Och Spine at New York Presbyterian Hospital, Weill Cornell Medicine, New York, New York, USA.
Lawrence J BonassarMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York, USA; Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York, USA. Electronic address: lb244@cornell.edu.

Funding

J. NRSA Training CoreTL1TR002386 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Genevieve Giny Fouda Amou ou · 2017 to 2026
$5.8M
Combined Engineering and Orthopaedics Training ProgramT32AR078751 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI MAHER, SUZANNE A., VAN DER MEULEN, MARJOLEIN C · 2021 to 2025
$1.7M
NCATS NIH HHS TL1 TR002386NIAMS NIH HHS T32 AR078751
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bioactive therapiesIntervertebral disc degenerationRegenerative medicineTissue engineering

Identifiers

PMID40561644
PMCPMC12344652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.