Evidence map›Paper›PMID 40561378›Full record

ArticleJournal of medical radiation sciences2025

Local Diagnostic Reference Levels in Digital Breast Tomosynthesis.

Peter Barnes, Michelle Kostidis, Julie Nguyen, Molly O'Donohue

Abstract read
In one paragraph

Article in Journal of medical radiation sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter BarnesAustin Health, Repatriation Hospital Campus, Heidelberg, Victoria, Australia.
Michelle KostidisAustin Health, Repatriation Hospital Campus, Heidelberg, Victoria, Australia.ORCID https://orcid.org/0000-0002-0334-762X
Julie NguyenAustin Health, Repatriation Hospital Campus, Heidelberg, Victoria, Australia.
Molly O'DonohueAustin Health, Repatriation Hospital Campus, Heidelberg, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiagnostic Reference Levels (DRLs) are a guideline to indicate whether the radiation administered during medical procedures performed under routine conditions is unusually low or high. Currently, there are no national DRLs in Australia for Digital Breast Tomosynthesis Mammography (DBT). Given the radiosensitivity of breast tissue, establishing DRLs for DBT is of great importance. This research aims to develop Local Diagnostic Reference Levels (LDRLs) for DBT that can be used as a guide for monitoring radiation delivery levels, and a Quality Assurance tool to assist in monitoring the performance of the mammography unit.

methodsAverage Glandular Dose (AGD) was collected from patient data through OpenREM software. Other data collected included breast density, compression force, compressed breast thickness (CBT), operative and treatment status. LDRLs were set using the 75th percentile (third quartile AGD values), categorised into four CBT ranges and compared against the median AGD values.

resultsLDRLs were similar for both craniocaudal and mediolateral oblique views. LDRLs for CBT ranges of 13-49 mm, 50-74 mm, 75-99 mm and 100-118 mm were calculated to be 1.5, 2.70, 3.90 and 4.70 mGy, respectively. There was no statistically significant correlation between breast density and AGD.

conclusionIt was found that CBT had a larger impact on dose than density. Significant differences were found between the LDRLs for each of the CBTs; therefore, setting a single LDRL for all CBTs may result in missing unacceptably high or low breast doses. LDRLs should be reviewed frequently to ensure the radiation dose patients receive is within optimal levels.

Indexed as

Breast NeoplasmsMammographyAdultAgedBreastDiagnostic Reference LevelsFemaleHumansMiddle AgedRadiation Dosagecompressiondiagnostic reference level (DRL)digital breast tomosynthesis (DBT)local diagnostic reference level (LDRL)mammography

Identifiers

PMID40561378
PMCPMC12420668

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.