ArticleJournal of occupational and environmental medicine2025
Polybrominated Diphenyl Ethers, Occupational Exposures, and Thyroid Function Among US and Canadian Firefighters: A Cross-sectional Study.
Article in Journal of occupational and environmental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Association of per- and polyfluoroalkyl substances (PFAS) exposure with cognitive function in firefighters.Journal of exposure science & environmental epidemiology · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveEvaluate the association between serum polybrominated diphenyl ether (PBDE) levels and thyroid anatomy and function in firefighters.
methodsTwo hundred fifty-nine firefighters provided a blood sample and underwent thyroid ultrasound. Blood serum levels were tested for thyroid function tests and PBDEs -47, -85, -99, -100, -153, and -154 (ng/g lipid weight). Ultrasonography documented structural characteristics. Bivariate associations between PBDE concentrations and demographic/occupational characteristics, thyroid function, and thyroid anatomic measures were determined using multivariable linear regression.
resultsA positive relationship between PBDE-47 and triiodothyronine ( P = 0.02) while an inverse relationship with free thyroxine ( P = 0.03) was observed. PBDE-47 was inversely associated with thyroid nodule size ( P = 0.03) and nodule aggressiveness ( P = 0.02). PBDE-47 was highest in western United States firefighters and lowest among sampled Canadians ( P = 0.01).
conclusionsPBDE-47 may contribute to thyroid dysregulation in firefighters. PBDE-47 levels differ across North America.
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