Evidence map›Paper›PMID 40561053›Full record

ArticlePloS one2025

Population attributable fraction of risk factors for anemia among children aged 6-59 months: A multilevel complex data analysis using modified poisson regression model in Sub-Saharan Africa.

Meklit Melaku Bezie, Beminate Lemma Seifu, Hiwot Altaye Asebe, Angwach Abrham Asnake, Yohannes Mekuria Negussie, Zufan Alamrie Asmare, Mamaru Melkam, Bezawit Melak Fente

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meklit Melaku BezieDepartment of Public Health Officer, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID 0009-0003-7490-2162
Beminate Lemma SeifuDepartment of Public Health, College of Medicine and Health Sciences, Samara University, Samara, Ethiopia.
Hiwot Altaye AsebeDepartment of Public Health, College of Medicine and Health Sciences, Samara University, Samara, Ethiopia.
Angwach Abrham AsnakeDepartment of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Yohannes Mekuria NegussieDepartment of Medicine, Adama General Hospital and Medical College, Adama, Ethiopia.ORCID 0000-0002-1332-670X
Zufan Alamrie AsmareDepartment of Ophthalmology, School of Medicine and Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Mamaru MelkamDepartment of Psychiatry, University of Gondar College of Medicine and Health Science, Gondar, Ethiopia.
Bezawit Melak FenteDepartment of General Midwifery, School of Midwifery, College of Medicine & Health, Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnemia among children under five remains a significant public health concern in sub-Saharan Africa (SSA). While numerous studies have examined its associated factors, limited evidence exists on the public health impact of modifiable risk factors. This study assessed the population-attributable fraction (PAF) of risk factors for anemia among children aged 6-59 months across 27 SSA countries.

methodsA secondary data analysis was conducted using Demographic and Health Survey (DHS) data from 27 SSA countries, including a weighted sample of 124,285 children. Data management and analysis were done using STATA-14 software. The presence of clustering was assessed using the Intra-cluster Correlation Coefficient (ICC), Median Odds Ratio (MOR), and Likelihood Ratio Test (LRT). A multilevel modified Poisson regression model was employed to estimate adjusted Prevalence Odds Ratios (aPOR) and the corresponding PAF with 95% Confidence Intervals (CI), and the Population Attributable Fraction (PAF) with the 95% CI was estimated using the aPOR and the prevalence of exposure.

resultsThe overall prevalence of anemia among children in SSA was 61.99% (95% CI: 61.73, 62.27). Significant risk factors included maternal anemia (PAF = 7.37%), low maternal education (PAF = 5.86% for no formal education), poor household wealth status (PAF = 3.52% for the poorest), lack of media exposure (PAF = 0.76%), child undernutrition (stunting PAF = 1.31%, underweight PAF = 0.84%), diarrheal (PAF = 1.19%) and febrile illness (PAF = 2.26%), and unimproved toilet facilities (PAF = 1.02%).

conclusionMaternal anemia, low maternal educational status, poverty, poor sanitation, inadequate media access, unimproved toilet facilities, and childhood illness significantly contribute to anemia in SSA. Targeted interventions to improve maternal and child health, enhance education, and ensure better nutrition and sanitation could help reduce childhood anemia in the region.

Indexed as

AnemiaAfrica South of the SaharaChild, PreschoolFemaleHealth SurveysHumansInfantMaleMultilevel AnalysisOdds RatioPoisson DistributionPrevalenceRisk FactorsSocioeconomic Factors

Identifiers

PMID40561053
PMCPMC12194221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.